Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | PPARG | P37231 | 10/20 | 0.57 |
| ▸ | EDNRA | P25101 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.54 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10443449 | 0.89 | RAB9A (0.66) | RAB9APPARGEDNRATSHRMAPK1 | |
| SCHEMBL10443492 | 0.86 | TNF (0.67) | RAB9APPARGEDNRALMNATP53 | |
| SCHEMBL8366932 | 0.83 | RAB9A (0.76) | RAB9ATSHRMAPK1AGTR1AGTR2 | |
| SCHEMBL10443037 | 0.82 | ALDH1A1 (0.72) | LMNATP53MAPTHTTSMN1; SMN2 | |
| SCHEMBL10443754 | 0.82 | ALDH1A1 (0.49) | RAB9APPARGAGTR1AGTR2LMNA | |
| SCHEMBL10443533 | 0.82 | LMNA (0.54) | MAPK1MEN1KMT2ALMNATP53 | |
| SCHEMBL10443933 | 0.81 | HDAC1 (0.57) | RAB9ATSHRMEN1KMT2ALMNA | |
| SCHEMBL8393405 | 0.81 | PPARG (0.84) | PPARGAGTR1AGTR2 | |
| SCHEMBL6361819 | 0.81 | RAB9A (0.78) | RAB9ATSHRMAPK1AGTR1AGTR2 | |
| SCHEMBL8366844 | 0.80 | RAB9A (0.76) | RAB9ATSHRMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0392317-A2 | Benzimidazoles, drugs containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1990-10-17 | — | — | EP | disclosed |