Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10443554 | 1.00 | REN (0.55) | RENBACE1 | |
| SCHEMBL10443715 | 0.90 | REN (0.55) | REN | |
| SCHEMBL10443798 | 0.90 | REN (0.55) | REN | |
| SCHEMBL10443609 | 0.86 | REN (0.61) | RENBACE1 | |
| SCHEMBL10443607 | 0.86 | REN (0.61) | RENBACE1 | |
| SCHEMBL7303652 | 0.86 | REN (0.57) | REN | |
| SCHEMBL10443717 | 0.85 | REN (0.45) | REN | |
| SCHEMBL10444206 | 0.85 | REN (0.71) | REN | |
| SCHEMBL10444394 | 0.84 | REN (0.50) | REN | |
| SCHEMBL7489578 | 0.84 | REN (0.53) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350163-A2 | Renin inhibitory peptides | BEECHAM GROUP PLC (GB) | 1990-01-10 | — | — | EP | disclosed |