SCHEMBL10443798

SCHEMBL10443798

CC(C)CNC(=O)C[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10443715 1.00 REN (0.55) REN
SCHEMBL10444046 0.90 REN (0.55) REN
SCHEMBL10443554 0.90 REN (0.55) REN
SCHEMBL10443344 0.85 REN (0.49) REN
SCHEMBL10443717 0.84 REN (0.45) REN
SCHEMBL10444206 0.83 REN (0.71) REN
SCHEMBL10443719 0.83 REN (0.47) REN
SCHEMBL10722785 0.83 REN (0.60) REN
SCHEMBL10722789 0.83 REN (0.60) REN
SCHEMBL9699599 0.83 REN (0.53) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0350163-A2 Renin inhibitory peptides BEECHAM GROUP PLC (GB) 1990-01-10 — — EP disclosed
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