Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1645211 | 0.77 | CA1 (0.62) | MEN1KMT2APOLBLMNASMN1; SMN2 | |
| SCHEMBL12845565 | 0.77 | MTNR1B (0.50) | MEN1KMT2APOLBSMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL29143533 | 0.76 | MEN1 (0.46) | MEN1KMT2APOLBLMNASMN1; SMN2 | |
| SCHEMBL631776 | 0.74 | KCNH3 (0.64) | MEN1KMT2APOLBLMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2249099 | 0.73 | KCNH3 (0.67) | MEN1KMT2APOLBLMNATSHR | |
| Sulfuric Acid SCHEMBL20984857 | 0.72 | KMT2A (0.51) | MEN1KMT2APOLBLMNASMN1; SMN2 | |
| SCHEMBL29564854 | 0.72 | SYK (0.59) | MEN1KMT2ALMNASMN1; SMN2TSHR | |
| SCHEMBL28885886 | 0.71 | KCNH3 (0.53) | MEN1KMT2APOLBLMNASMN1; SMN2 | |
| SCHEMBL309673 | 0.71 | LMNA (0.60) | MEN1KMT2APOLBLMNASMN1; SMN2 | |
| SCHEMBL10989610 | 0.71 | KCNH3 (0.53) | MEN1KMT2APOLBLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376166-A1 | Condensed quinoline system compound and process of preparation thereof | MECT CORPORATION (JP) | 1990-07-04 | — | — | EP | disclosed |