SCHEMBL10445593

SCHEMBL10445593

CCCCC=CCCCCCCCCCS(=O)(=O)O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.70
PPARA Q07869 3/20 0.55
F7 P08709 2/20 0.52
F3 P13726 2/20 0.52
FAAH O00519 4/20 0.52
TRPV1 Q8NER1 1/20 0.48
TERT O14746 3/20 0.47
MAPT P10636 2/20 0.47
BLM P54132 2/20 0.47
HSD17B10 Q99714 2/20 0.47
FABP4 P15090 2/20 0.47
GMNN O75496 1/20 0.47
USP2 O75604 1/20 0.47
LMNA P02545 1/20 0.47
CYP1A2 P05177 1/20 0.47
POLB P06746 1/20 0.47
CYP2C9 P11712 1/20 0.47
ALOX15 P16050 1/20 0.47
APEX1 P27695 1/20 0.47
CYP2C19 P33261 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10445375 1.00 EPHX2 (0.70) EPHX2PPARAF7F3FAAH
SCHEMBL10445592 1.00 EPHX2 (0.70) EPHX2PPARAF7F3FAAH
SCHEMBL10445591 1.00 EPHX2 (0.70) EPHX2PPARAF7F3FAAH
SCHEMBL2219389 0.96 EPHX2 (0.75) EPHX2PPARAF7F3FAAH
SCHEMBL4092435 0.96 EPHX2 (0.75) EPHX2PPARAF7F3FAAH
SCHEMBL9777847 0.96 EPHX2 (0.75) EPHX2PPARAF7F3FAAH
SCHEMBL11370740 0.96 EPHX2 (0.75) EPHX2PPARAF7F3FAAH
SCHEMBL1962429 0.96 EPHX2 (0.75) EPHX2PPARAF7F3FAAH
SCHEMBL8349583 0.96 EPHX2 (0.75) EPHX2PPARAF7F3FAAH
SCHEMBL11370737 0.96 EPHX2 (0.75) EPHX2PPARAF7F3FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250154102-A1 CYCLIC LIPIDS AND METHODS OF USE THEREOF RENAGADE THERAPEUTICS MAN INC (US) 2025-05-15 US disclosed
EP-4522646-A2 APOE LIPOPROTEIN SYSTEMS Kisbee Therapeutics, Inc. (US) 2025-03-19 EP disclosed
EP-4452934-A1 IONIZABLE DISULFIDE LIPIDS AND LIPID NANOPARTICLES DERIVED THEREFROM Providence Therapeutics Holdings Inc. (CA) 2024-10-30 EP disclosed
EP-4452928-A1 CONSTRAINED LIPIDS AND METHODS OF USE THEREOF Renagade Therapeutics Management Inc. (US) 2024-10-30 EP disclosed
EP-4402123-A1 CYCLIC LIPIDS AND METHODS OF USE THEREOF Renagade Therapeutics Management Inc. (US) 2024-07-24 EP disclosed
WO-2023220387-A2 APOE LIPOPROTEIN SYSTEMS KISBEE THERAPEUTICS, INC. (US) 2023-11-16 WO disclosed
WO-2023196931-A1 CYCLIC LIPIDS AND LIPID NANOPARTICLES (LNP) FOR THE DELIVERY OF NUCLEIC ACIDS OR PEPTIDES FOR USE IN VACCINATING AGAINST INFECTIOUS AGENTS RENAGADE THERAPEUTICS MANAGEMENT INC. (US) 2023-10-12 WO disclosed
WO-2023137550-A1 COMPOSITIONS AND METHODS FOR THE PREVENTION AND/OR TREATMENT OF COVID-19 PROVIDENCE THERAPEUTICS HOLDINGS INC. (CA) 2023-07-27 WO disclosed
WO-2023122752-A1 CONSTRAINED LIPIDS AND METHODS OF USE THEREOF RENAGADE THERAPEUTICS MANAGEMENT INC. (US) 2023-06-29 WO disclosed
US-20230202977-A1 CYCLIC LIPIDS AND METHODS OF USE THEREOF RENAGADE THERAPEUTICS MANAGEMENT INC. 2023-06-29 US disclosed
WO-2023115221-A1 IONIZABLE DILSULFIDE LIPIDS AND LIPID NANOPARTICLES DERIVED THEREFROM PROVIDENCE THERAPEUTICS HOLDINGS INC. (CA) 2023-06-29 WO disclosed
WO-2023050003-A1 COMPOSITIONS AND METHODS FOR THE PREVENTION AND/OR TREATMENT OF COVID-19 PROVIDENCE THERAPEUTICS HOLDINGS INC. (CA) 2023-04-06 WO disclosed
WO-2023044333-A1 CYCLIC LIPIDS AND METHODS OF USE THEREOF RENAGADE THERAPEUTICS MANAGEMENT INC. (US) 2023-03-23 WO disclosed
WO-2023023055-A1 COMPOSITIONS AND METHODS FOR OPTIMIZING TROPISM OF DELIVERY SYSTEMS FOR RNA RENAGADE THERAPEUTICS MANAGEMENT INC. (US) 2023-02-23 WO disclosed
EP-0355842-A2 External preparation Sansho Seiyaku Co., Ltd. (JP) 1990-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250154102-A1 CYCLIC LIPIDS AND METHODS OF USE THEREOF SGMS1, SGMS2, LNPEP EPHX2 2176/4885PPARA 1870/4885F7 1893/4885
US-20230202977-A1 CYCLIC LIPIDS AND METHODS OF USE THEREOF SGMS1, SGMS2, LNPEP EPHX2 2176/4885PPARA 1870/4885F7 1893/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.