SCHEMBL1044569

SCHEMBL1044569

Nc1cccc(C(=O)c2ccccc2)c1O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.71
GAA P10253 2/20 0.71
MMP2 P08253 1/20 0.66
AKR1C3 P42330 1/20 0.53
POLB P06746 1/20 0.51
HSD17B10 Q99714 2/20 0.49
ALDH1A1 P00352 2/20 0.49
MEN1 O00255 2/20 0.49
USP2 O75604 2/20 0.49
KMT2A Q03164 2/20 0.49
KDM4E B2RXH2 1/20 0.49
ALOX15 P16050 1/20 0.49
MAPK1 P28482 1/20 0.49
LMNA P02545 1/20 0.49
GLA P06280 1/20 0.49
PBRM1 Q86U86 1/20 0.48
ADORA1 P30542 1/20 0.47
ATM Q13315 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL720049 0.86 MMP2 (0.72) MAPTGAAMMP2HSD17B10ALDH1A1
SCHEMBL28746 0.84 MAPT (1.00) MAPTGAAAKR1C3POLBHSD17B10
SCHEMBL29602136 0.84 MAPT (1.00) MAPTGAAAKR1C3POLBHSD17B10
SCHEMBL8395171 0.83 MMP2 (0.63) MAPTGAAMMP2HSD17B10ALDH1A1
SCHEMBL11033943 0.83 MMP2 (0.75) MAPTGAAMMP2AKR1C3POLB
SCHEMBL112508 0.82 MAPT (0.74) MAPTGAAMMP2AKR1C3POLB
SCHEMBL10937897 0.82 MAPT (0.74) MAPTGAAMMP2AKR1C3POLB
Benzene SCHEMBL28303083 0.82 MAPT (0.74) MAPTGAAMMP2AKR1C3POLB
SCHEMBL29786713 0.82 MAPT (0.74) MAPTGAAMMP2AKR1C3POLB
SCHEMBL27481713 0.82 MAPK13 (0.59) MAPTGAAMMP2KMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 267 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105431130-A Cosmetic or dermatological composition comprising a merocyanine, an organic UVB-screening agent and an additional organic UVA-screening agent L'OREAL S A 2016-03-23 CN claimed
CN-105307631-A Cosmetic or dermatological composition comprising a merocyanine and a uva-screening agent of the amino-substituted 2-hydroxybenzophenone type and/or a hydrophilic organic uva-screening agent OREAL 2016-02-03 CN claimed
US-20070219275-A1 Use of Benzophenone Uv Filters for Preventing Tanning BASCHONG WERNER 2007-09-20 US claimed
EP-1737419-A2 USE OF BENZOPHENONE UV FILTERS FOR PREVENTING TANNING Ciba SC Holding AG (CH) 2007-01-03 EP claimed
WO-2005094772-A2 USE OF BENZOPHENONE UV FILTERS FOR PREVENTING TANNING CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-10-13 WO claimed
CN-1554325-A Use of of aminosubstituted hydroxybenzophenones as photostable uv-filter in cosmetic and pharmaceutical preparations BASF 2004-12-15 CN claimed
CN-1425366-A Anti-sun light cosmetic composition based on sun screening agent synergic mixture and its use OREAL (FR) 2003-06-25 CN claimed
CN-1425368-A Anti-sun light cosmetic composition based on synergetic function screening agent mixture and use OREAL (FR) 2003-06-25 CN claimed
CN-1424020-A Sun screener containing dibenzoyl methane derivative and amino substituted 2-hydroxy benzophenone derivative OREAL (FR) 2003-06-18 CN claimed
CN-1273088-A Use of amino-substituted hydroxybenzophenones as photostable UV filters in cosmetic and pharmaceutical preparations BASF AG (DE) 2000-11-15 CN claimed
CN-118434357-A Analyte sensor and method for producing an analyte sensor 豪夫迈·罗氏有限公司 2024-08-02 CN disclosed
EP-3458162-B1 MICRO-PARTICULATE ORGANIC UV ABSORBER COMPOSITION BASF SE (DE) 2024-07-10 EP disclosed
CN-117979899-A Sensor with varying stiffness 豪夫迈·罗氏有限公司 2024-05-03 CN disclosed
CN-117858663-A Films with biodegradable polymers 豪夫迈·罗氏有限公司 2024-04-09 CN disclosed
CN-117836618-A Opening formation in a film 豪夫迈·罗氏有限公司 2024-04-05 CN disclosed
EP-0896531-A1 IL-8 RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1999-02-17 EP disclosed
US-5780483-A IL-8 receptor antagonists SMITHKLINE BEECHAM CORPORATION (US) 1998-07-14 US disclosed
EP-0809492-A1 IL-8 RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1997-12-03 EP disclosed
WO-1997029743-A1 IL-8 RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1997-08-21 WO disclosed
WO-1996025157-A1 IL-8 RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1996-08-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070219275-A1 Use of Benzophenone Uv Filters for Preventing Tanning C1R, CBR3, AOC3 MAPT 4671/4885GAA 2029/4885MMP2 1295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.