Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 10/20 | 0.52 |
| ▸ | CES1 | P23141 | 9/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6691083 | 0.84 | MAPT (0.67) | MMP2GAAMAPTCES2CES1 | |
| SCHEMBL1885623 | 0.83 | MAPT (0.55) | MMP2GAAMAPTCES2CES1 | |
| SCHEMBL1044569 | 0.83 | MAPT (0.71) | MMP2GAAMAPTMAPK1PBRM1 | |
| Benzil SCHEMBL3796381 | 0.82 | MAPT (0.64) | MMP2GAAMAPTCES2CES1 | |
| Hydrochloric Acid SCHEMBL27739689 | 0.81 | MAPT (0.53) | MMP2GAAMAPTCES2CES1 | |
| SCHEMBL28110230 | 0.81 | MAPT (0.53) | MMP2GAAMAPTCES2CES1 | |
| SCHEMBL9797520 | 0.81 | CES2 (0.56) | GAAMAPTCES2CES1ALB | |
| SCHEMBL29547161 | 0.78 | MMP2 (1.00) | MMP2GAAMAPTRAB9AALB | |
| SCHEMBL204392 | 0.78 | MMP2 (1.00) | MMP2GAAMAPTRAB9AALB | |
| SCHEMBL2877065 | 0.78 | MAPT (0.58) | MMP2GAAMAPTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748310-B1 | DIESTERS OF CARBONIC ACID ENDOWED WITH ANTIVIRAL AND ANTI-INFLAMMATORY ACTIVITY | ITALFARMACO SPA (IT) | 1999-06-02 | — | — | EP | disclosed |
| US-5827881-A | ADMINISTERING FOR TREATMENT OF VIRAL DISEASES OR AS ANTIINFLAMMATORY AGENTS | ITALFARMACO S.P.A. (IT) | 1998-10-27 | — | — | US | disclosed |
| CN-1142222-A | Diesters of carbonic acid endowed with antiviral and anti-inflammatory activity | ITALFARMACO SPA (IT) | 1997-02-05 | — | — | CN | disclosed |
| EP-0748310-A1 | DIESTERS OF CARBONIC ACID ENDOWED WITH ANTIVIRAL AND ANTI-INFLAMMATORY ACTIVITY | ITALFARMACO S.p.A. (IT) | 1996-12-18 | — | — | EP | disclosed |
| WO-1995023128-A1 | DIESTERS OF CARBONIC ACID ENDOWED WITH ANTIVIRAL AND ANTI-INFLAMMATORY ACTIVITY | ITALFARMACO S.P.A. (IT) | 1995-08-31 | — | — | WO | disclosed |