Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 8/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BPTF | Q12830 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770625 | 0.83 | KDM4E (0.43) | KDM4EALDH1A1HPGDACHETSHR | |
| SCHEMBL9770499 | 0.75 | KDM4E (0.45) | KDM4EALDH1A1HPGDACHETSHR | |
| SCHEMBL9770449 | 0.65 | CTSK (0.49) | KDM4EALDH1A1ACHETSHRMAPK1 | |
| SCHEMBL21963155 | 0.62 | ACHE (0.55) | KDM4EALDH1A1ACHETSHRMAPK1 | |
| Ipidacrine SCHEMBL28251 | 0.59 | ACHE (1.00) | KDM4EALDH1A1ACHETSHRMAPK1 | |
| Ipidacrine SCHEMBL29382648 | 0.59 | ACHE (1.00) | KDM4EALDH1A1ACHETSHRMAPK1 | |
| SCHEMBL21962904 | 0.59 | ACHE (0.50) | KDM4EALDH1A1ACHETSHRMAPK1 | |
| SCHEMBL9583264 | 0.59 | ACHE (0.67) | KDM4EALDH1A1ACHETSHRMAPK1 | |
| Ipidacrine SCHEMBL1032513 | 0.58 | ACHE (0.95) | KDM4EALDH1A1ACHETSHRMAPK1 | |
| Ipidacrine SCHEMBL7536973 | 0.58 | ACHE (0.95) | KDM4EALDH1A1ACHETSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0361489-A2 | Novel 3,4-diaminoquinoline and pyridine compounds | Chugai Seiyaku Kabushiki Kaisha (JP) | 1990-04-04 | — | — | EP | disclosed |