Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 8/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.42 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.42 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770566 | 0.78 | KDM4E (0.55) | CTSKLMNAHTTALDH1A1TSHR | |
| SCHEMBL16098744 | 0.69 | CDK5 (0.53) | ACHELMNAHTTUSP2POLB | |
| SCHEMBL9770625 | 0.68 | KDM4E (0.43) | CTSKACHELMNABCHEALDH1A1 | |
| SCHEMBL10445752 | 0.65 | KDM4E (0.40) | ACHELMNABCHEALDH1A1TSHR | |
| SCHEMBL23975752 | 0.65 | KMT2A (0.51) | ACHELMNAHTTUSP2POLB | |
| SCHEMBL26115603 | 0.65 | LMNA (0.50) | LMNAHTTPOLBALDH1A1KDM4E | |
| SCHEMBL27431420 | 0.65 | ACHE (0.51) | ACHELMNAUSP2POLBBCHE | |
| SCHEMBL14128251 | 0.64 | LMNA (0.83) | LMNAHTTPOLBALDH1A1KDM4E | |
| SCHEMBL9770560 | 0.64 | ALDH1A1 (0.54) | LMNAHTTUSP2ALDH1A1TSHR | |
| SCHEMBL19623540 | 0.64 | PIK3CA (0.57) | LMNAALDH1A1TSHRKDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019574-A | 3,4-diaminoquinoline and 3,4-diamino-5,6,7,8-tetrahydroquinoline compounds useful for improving psychoneural function | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1991-05-28 | — | — | US | disclosed |
| EP-0361489-A2 | Novel 3,4-diaminoquinoline and pyridine compounds | Chugai Seiyaku Kabushiki Kaisha (JP) | 1990-04-04 | — | — | EP | disclosed |