SCHEMBL10445802

SCHEMBL10445802

O=C([O-])CC(O)(O)C(=O)[O-].O=C([O-])CC(O)(O)C(=O)[O-].O=C([O-])CC(O)(O)C(=O)[O-].[Bi+3].[Bi+3]

nearest known ligand 0.55

Known targets — ChEMBL curated mechanism

HRH2

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CA4 P22748 3/20 0.55
CASP1 P29466 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1324317 0.94 CA4 (0.55) CA4CASP1
SCHEMBL7603816 0.94 CA4 (0.62) CA4CASP1
SCHEMBL1324316 0.94 CA4 (0.62) CA4CASP1
SCHEMBL7969654 0.92 CA4 (0.59) CA4CASP1
Citric Acid SCHEMBL362816 0.77 CA4 (0.89) CA4CASP1
Citric Acid SCHEMBL693006 0.77 CA4 (0.89) CA4CASP1
Citric Acid SCHEMBL7921325 0.77 CA4 (0.89) CA4CASP1
Citric Acid SCHEMBL41916 0.77 CA4 (0.89) CA4CASP1
Citric Acid SCHEMBL18131942 0.77 CA4 (0.89) CA4CASP1
Citric Acid SCHEMBL1231331 0.77 CA4 (0.89) CA4CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0367484-A1 Carboxylic acid derivates GLAXO GROUP LIMITED (GB) 1990-05-09 EP claimed