SCHEMBL1044582

SCHEMBL1044582

CCCCCCCCCCCCCCCC(=O)OCCN1CC[N+](CCO)=C1CCCCCCCCCCCCCCC

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.48
DNM1 Q05193 1/20 0.39
EPHX2 P34913 2/20 0.36
PRKCA P17252 3/20 0.36
PAM P19021 2/20 0.36
KDM4E B2RXH2 1/20 0.36
DUSP3 P51452 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
LMNA P02545 1/20 0.36
MGLL Q99685 1/20 0.36
PRSS1 P07477 1/20 0.36
PRSS2 P07478 1/20 0.36
PRSS3 P35030 1/20 0.36
CNR2 P34972 2/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL888280 0.99 DGKA (0.47) DGKADNM1EPHX2PRKCAPAM
Hydrochloric Acid SCHEMBL18209371 0.99 DGKA (0.47) DGKADNM1EPHX2PRKCAPAM
Water SCHEMBL6549696 0.93 MGLL (0.46) DGKAEPHX2PRKCAMGLLCNR2
Hydrochloric Acid SCHEMBL4074680 0.93 MGLL (0.46) DGKAEPHX2PRKCAMGLLCNR2
SCHEMBL441410 0.80 MGLL (0.46) DGKAEPHX2PRKCAMGLLCNR2
SCHEMBL19133947 0.80 MGLL (0.46) DGKAEPHX2PRKCAMGLLCNR2
Hydrochloric Acid SCHEMBL421820 0.79 MGLL (0.45) DGKAEPHX2PRKCAMGLLCNR2
Hydrochloric Acid SCHEMBL3281364 0.79 MGLL (0.45) DGKAEPHX2PRKCAMGLLCNR2
SCHEMBL16607665 0.79 DGKA (0.45) DGKAEPHX2PRKCAMGLL
SCHEMBL19169673 0.78 DGKA (0.44) DGKAEPHX2PRKCAMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3397244-B1 TREATMENT OF BREAST CANCER USING A COMBINATION OF A CATIONIC LIPOSOMAL FORMULATION OF TAXANE, A NON-LIPOSOMAL FORMULATION OF TAXANE AND A FURTHER ACTIVE AGENT SYNCORE BIOTECHNOLOGY CO LTD (TW) 2021-10-06 EP claimed
EP-3939572-B1 VEHICLES FOR CONTROLLED DELIVERY OF DIFFERENT PHARMACEUTICAL AGENTS UNIV YALE (US) 2024-03-27 EP disclosed
EP-3520780-B1 VEHICLES FOR CONTROLLED DELIVERY OF DIFFERENT PHARMACEUTICAL AGENTS UNIV YALE (US) 2023-07-26 EP disclosed
EP-3939572-A1 VEHICLES FOR CONTROLLED DELIVERY OF DIFFERENT PHARMACEUTICAL AGENTS Yale University, Inc. (US) 2022-01-19 EP disclosed
EP-3520780-A1 VEHICLES FOR CONTROLLED DELIVERY OF DIFFERENT PHARMACEUTICAL AGENTS Yale University (US) 2019-08-07 EP disclosed
EP-2836234-B1 VEHICLES FOR CONTROLLED DELIVERY OF DIFFERENT PHARMACEUTICAL AGENTS UNIV YALE (US) 2019-06-12 EP disclosed
EP-2286795-A1 Method of producing a cationic liposomal preparation comprising a lipophilic compound MediGene AG (DE) 2011-02-23 EP disclosed
EP-2277507-A1 Method of producing a cationic liposomal preparation comprising a lipophilic compound MediGene AG (DE) 2011-01-26 EP disclosed
EP-2200637-A2 LONG INTERSPERSED NUCLEAR ELEMENT POLYPEPTIDE COMPOSITIONS AND METHODS OF USE THEREOF The J. David Gladstone Institutes (US) 2010-06-30 EP disclosed
EP-2108362-A2 Method of producing a cationic liposomal preparation comprising a lipophilic compound Medigene AG (DE) 2009-10-14 EP disclosed
EP-1530465-B1 METHOD OF PRODUCING A CATIONIC LIPOSOMAL PREPARATION COMPRISING A LIPOPHILIC COMPOUND MEDIGENE AG (DE) 2009-09-30 EP disclosed
WO-2009038756-A2 LONG INTERSPERSED NUCLEAR ELEMENT POLYPEPTIDE COMPOSITIONS AND METHODS OF USE THEREOF THE J. DAVID GLADSTONE INSTITUTES (US) 2009-03-26 WO disclosed
EP-1767192-A2 Cationic lipid compositions targeting angiogenic endothelial cells The Regents of the University of California (US) 2007-03-28 EP disclosed
EP-1014945-A1 CATIONIC LIPID COMPOSITIONS TARGETING ANGIOGENIC ENDOTHELIAL CELLS The Regents of the University of California (US) 2000-07-05 EP disclosed
WO-1998040052-A9 CATIONIC LIPID COMPOSITIONS TARGETING ANGIOGENIC ENDOTHELIAL CELLS UNIV CALIFORNIA (US) 1999-09-02 WO disclosed
WO-1998040052-A1 CATIONIC LIPID COMPOSITIONS TARGETING ANGIOGENIC ENDOTHELIAL CELLS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1998-09-17 WO disclosed