SCHEMBL441410

SCHEMBL441410

CCCCCCCCC=CCCCCCCCC(=O)OCCN1CC[N+](CCO)=C1C(=O)CCCCCCCC=CCCCCCCCC

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.46
EPHX2 P34913 1/20 0.43
DGKA P23743 2/20 0.42
PRKCA P17252 3/20 0.40
PRKCE Q02156 1/20 0.40
PRKCQ Q04759 1/20 0.40
PRKCD Q05655 1/20 0.40
FAAH O00519 1/20 0.40
ALDH1A1 P00352 1/20 0.40
MAPT P10636 1/20 0.40
THRB P10828 1/20 0.40
CNR1 P21554 1/20 0.40
CNR2 P34972 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19133947 1.00 MGLL (0.46) MGLLEPHX2DGKAPRKCAPRKCE
Hydrochloric Acid SCHEMBL421820 0.99 MGLL (0.45) MGLLEPHX2DGKAPRKCAPRKCE
Hydrochloric Acid SCHEMBL3281364 0.99 MGLL (0.45) MGLLEPHX2DGKAPRKCAPRKCE
Hydrochloric Acid SCHEMBL421819 0.86 MGLL (0.46) MGLLEPHX2DGKAPRKCAPRKCE
Hydrochloric Acid SCHEMBL4074680 0.86 MGLL (0.46) MGLLEPHX2DGKAPRKCAPRKCE
Water SCHEMBL6549696 0.86 MGLL (0.46) MGLLEPHX2DGKAPRKCAPRKCE
SCHEMBL1044582 0.80 DGKA (0.48) MGLLEPHX2DGKAPRKCACNR2
Hydrochloric Acid SCHEMBL18209371 0.79 DGKA (0.47) MGLLEPHX2DGKAPRKCACNR2
Hydrochloric Acid SCHEMBL888280 0.79 DGKA (0.47) MGLLEPHX2DGKAPRKCACNR2
Hydrochloric Acid SCHEMBL25292894 0.79 MGLL (0.43) MGLLEPHX2DGKAPRKCAPRKCE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4312989-A1 FORMULATION FOR MESSENGER RNA DELIVERY INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSERM (FR) 2024-02-07 EP claimed
WO-2022207736-A1 FORMULATION FOR MESSENGER RNA DELIVERY INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 2022-10-06 WO claimed
EP-3328423-B1 ENHANCED IMMUNE RESPONSE IN FISH BAYER ANIMAL HEALTH GMBH (DE) 2021-05-26 EP claimed
EP-3377114-B1 IMMUNOGENIC COMPOSITION IN THE FORM OF AN EMULSION COMPRISING TWO DISPERSED PHASES, ONE COMPRISING AN ANTIGEN AND THE OTHER COMPRISING AN IMMUNOSTIMULATING AGENT COMMISSARIAT ENERGIE ATOMIQUE (FR) 2020-07-08 EP claimed
EP-2763657-B1 MOLECULE MIXTURE COMPRISING AN AMPHIPATHIC MOLECULE TYPE A, WHICH HAS A POSITIVE TOTAL CHARGE IN THE HYDROPHILIC RANGE, AND AN AMPHIPATHIC MOLECULE TYPE B AND A POLYPHENOL C, METHOD FOR PRODUCING SAID MOLECULE MIXTURE AND USE THEREOF FORSCHUNGSZENTRUM JUELICH GMBH (DE) 2020-03-25 EP claimed
US-10597700-B2 High-throughput screening method for the identification of biomarkers, therapeutic targets or therapeutic agents COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2020-03-24 US claimed
US-10253315-B2 Method for transfection of nucleic acids into eukaryotic cells in 3D scaffold COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2019-04-09 US claimed
EP-3377114-A1 IMMUNOGENIC COMPOSITION IN THE FORM OF AN EMULSION COMPRISING TWO DISPERSED PHASES, ONE COMPRISING AN ANTIGEN AND THE OTHER COMPRISING AN IMMUNOSTIMULATING AGENT Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) 2018-09-26 EP claimed
EP-2890364-B1 FORMULATION FOR THE DELIVERY OF NUCLEOTIDE SEQUENCES THAT CAN MODULATE ENDOGENOUS INTERFERING RNA MECHANISMS Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) 2018-01-10 EP claimed
EP-2961423-B1 IMMUNOGENIC COMPOSITION IN EMULSION FORM Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) 2017-07-26 EP claimed
US-20150258022-A1 Formulation for the Delivery of Nucleotide Sequences That Can Modulate Endogenous Interfering RNA Mechanisms COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2015-09-17 US claimed
EP-2890364-A1 FORMULATION FOR THE DELIVERY OF NUCLEOTIDE SEQUENCES THAT CAN MODULATE ENDOGENOUS INTERFERING RNA MECHANISMS Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) 2015-07-08 EP claimed
WO-2014131809-A1 IMMUNOGENIC COMPOSITION IN EMULSION FORM Commissariat à l'énergie atomique et aux énergies alternatives (FR) 2014-09-04 WO claimed
WO-2014083205-A1 HIGH-THROUGHPUT SCREENING METHOD FOR THE IDENTIFICATION OF BIOMARKERS, THERAPEUTIC TARGETS OR THERAPEUTIC AGENTS Commissariat à l'énergie atomique et aux énergies alternatives (FR) 2014-06-05 WO claimed
WO-2014032953-A1 FORMULATION FOR THE DELIVERY OF NUCLEOTIDE SEQUENCES THAT CAN MODULATE ENDOGENOUS INTERFERING RNA MECHANISMS COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2014-03-06 WO claimed
EP-1648379-A4 VACCINES USING PATTERN RECOGNITION RECEPTOR-LIGAND:LIPID COMPLEXES JUVARIS BIOTHERAPEUTICS INC (US) 2008-01-16 EP claimed
EP-1648379-A2 VACCINES USING PATTERN RECOGNITION RECEPTOR-LIGAND:LIPID COMPLEXES Juvaris Biotherapeutics, Inc. (US) 2006-04-26 EP claimed
WO-2005013891-A2 VACCINES USING PATTERN RECOGNITION RECEPTOR-LIGAND:LIPID COMPLEXES JUVARIS BIOTHERAPEUTICS, INC. (US) 2005-02-17 WO claimed
US-20050013812-A1 Vaccines using pattern recognition receptor-ligand:lipid complexes NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2005-01-20 US claimed
EP-0832270-B1 CATIONIC LIPID:DNA COMPLEXES FOR GENE TARGETING VALENTIS INC (US) 2004-10-27 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150258022-A1 Formulation for the Delivery of Nucleotide Sequences That Can Modulate Endogenous Interfering RNA Mechanisms NSUN2, RNMT, SNRPA MGLL 2546/4885EPHX2 4171/4885DGKA 881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.