SCHEMBL10445848

SCHEMBL10445848

CCCCCCCCOc1ccc(COC2(O)C=CC(c3ccccc3)=CC2)cc1

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NR5A1 Q13285 1/20 0.41
LTA4H P09960 1/20 0.40
PLA2G4B P0C869 3/20 0.39
RARB P10826 3/20 0.39
ITGB1 P05556 1/20 0.38
ITGA4 P13612 1/20 0.38
TP53 P04637 1/20 0.38
TSHR P16473 1/20 0.38
S1PR1 P21453 5/20 0.38
S1PR3 Q99500 4/20 0.38
S1PR5 Q9H228 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21224653 0.85 NR5A1 (0.40) NR5A1TSHR
SCHEMBL10449057 0.85 NR5A1 (0.40) NR5A1TSHR
SCHEMBL28464418 0.85 NR5A1 (0.40) NR5A1TSHR
SCHEMBL28472097 0.83 NR5A1 (0.37) NR5A1LTA4HTSHR
SCHEMBL8422558 0.82 ALDH1A1 (0.33) TSHR
SCHEMBL10448680 0.82 RARB (0.47) PLA2G4BRARBTP53TSHR
SCHEMBL27973883 0.80 CETP (0.38) NR5A1LTA4HTP53TSHR
SCHEMBL9514230 0.78 NR5A1 (0.42) NR5A1LTA4HTP53
SCHEMBL8969959 0.77 FAAH (0.47) LTA4HPLA2G4BRARBTP53TSHR
SCHEMBL9778751 0.76 RARB (0.42) NR5A1LTA4HRARBTP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0351782-A2 Optically active compounds liquid crystal composition containing said compound, and liquid crystal optical modulator using said composition HITACHI, LTD. (JP) 1990-01-24 EP disclosed