SCHEMBL8285443

SCHEMBL8285443

COC1=C(Cl)C(=O)c2ccccc2C1=O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 12/20 0.71
ALDH1A1 P00352 9/20 0.71
KDM4E B2RXH2 8/20 0.71
LMNA P02545 7/20 0.71
POLB P06746 7/20 0.71
HPGD P15428 6/20 0.71
TDP1 Q9NUW8 5/20 0.71
SMN1; SMN2 Q16637 4/20 0.71
RAB9A P51151 4/20 0.71
CDC25A P30304 3/20 0.71
CDC25B P30305 3/20 0.71
MAP2K7 O14733 1/20 0.71
GMNN O75496 1/20 0.71
TP53 P04637 1/20 0.71
CYP1A2 P05177 1/20 0.71
CYP3A4 P08684 1/20 0.71
CYP2D6 P10635 1/20 0.71
CYP2C9 P11712 1/20 0.71
ALOX15 P16050 1/20 0.71
CYP2C19 P33261 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10901421 0.98 MAPT (0.75) MAPTALDH1A1KDM4ELMNAPOLB
SCHEMBL10863927 0.84 MAPT (0.50) MAPTALDH1A1KDM4ELMNAPOLB
SCHEMBL29545010 0.84 MAPT (1.00) MAPTALDH1A1KDM4ELMNAPOLB
SCHEMBL571557 0.84 MAPT (1.00) MAPTALDH1A1KDM4ELMNAPOLB
SCHEMBL9849847 0.81 NSD2 (0.74) MAPTALDH1A1KDM4ELMNAPOLB
SCHEMBL9324815 0.79 IDO1 (0.58) MAPTALDH1A1KDM4ELMNAPOLB
Dichlon SCHEMBL45723 0.78 IDO1 (1.00) MAPTALDH1A1KDM4ELMNAPOLB
SCHEMBL4908282 0.78 MAPT (0.48) MAPTALDH1A1KDM4ELMNAPOLB
Dichlon SCHEMBL29360991 0.78 IDO1 (1.00) MAPTALDH1A1KDM4ELMNAPOLB
Dichlon SCHEMBL9751236 0.78 IDO1 (1.00) MAPTALDH1A1KDM4ELMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0098020-A2 Imaging film and film-forming composition, method for recording electromagnetic radiation, quinone compounds and method of synthesizing quinone compounds ENERGY CONVERSION DEVICES, INC. (US) 1984-01-11 EP claimed
US-4324852-A REDOX COUPLES EASTMAN KODAK COMPANY (US) 1982-04-13 US claimed
US-4201588-A NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, CARBAZIDES OR QUINONES AS PHOTOREDUCTANT; EXTERNAL HYDROGEN SOURCE EASTMAN KODAK COMPANY (US) 1980-05-06 US claimed
US-4195998-A NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, QUINONE OR CARBAZIDE PHOTOREDUCTANT EASTMAN KODAK COMPANY (US) 1980-04-01 US claimed
WO-2005053609-A2 METHODS OF NAD+-DEPENDENT DEACETYLASE INHIBITORS GUILFORD PHARMACEUTICALS INC. (US) 2005-06-16 WO disclosed
EP-0383536-A2 Thermo-sensitive transfer printing medium SEIKO INSTRUMENTS INC. (JP) 1990-08-22 EP disclosed
EP-0100126-B1 METHOD FOR RECORDING ELECTROMAGNETIC RADIATION ENERGY CONVERSION DEVICES, INC. (US) 1988-11-30 EP disclosed
US-4698184-A Tellurium imaging composition including improved reductant precursor and method ENERGY CONVERSION DEVICES, INC. (US) 1987-10-06 US disclosed
US-4592867-A Synthesis method for reductant precursor ENERGY CONVERSION DEVICES, INC. (US) 1986-06-03 US disclosed
EP-0178903-A2 Improved tellurium imaging composition and film including imide or ammonium salt ENERGY CONVERSION DEVICES, INC. (US) 1986-04-23 EP disclosed
US-4535055-A DIOLS, QUINONES, ORGANO TELLURIUM COMPOUNDS ENERGY CONVERSION DEVICES, INC. (US) 1985-08-13 US disclosed
US-4532078-A 2,3-Diisopropoxy-1,4-naphthoquinone ENERGY CONVERSION DEVICES, INC. (US) 1985-07-30 US disclosed
EP-0098019-A2 Imaging film and composition including a tellurium compound and method for recording electromagnetic radiation ENERGY CONVERSION DEVICES, INC. (US) 1984-01-11 EP disclosed
EP-0098020-A2 Imaging film and film-forming composition, method for recording electromagnetic radiation, quinone compounds and method of synthesizing quinone compounds ENERGY CONVERSION DEVICES, INC. (US) 1984-01-11 EP disclosed
EP-0098018-A2 Imaging film and composition employing an organo-metallic compound and method for recording electromagnetic radiation ENERGY CONVERSION DEVICES, INC. (US) 1984-01-11 EP disclosed
US-4332884-A USING A DIOXIME CHELATING AGENT RICOH CO., LTD. (JP) 1982-06-01 US disclosed
US-4315068-A CONTAINING A COBALT-AMMINE COMPLEX AND A DIOXIME OR A BISIMIDAZOLIN-3-ONE CHELATING AGENT; STABILITY; COLOR DILMS RICOH CO., LTD. (JP) 1982-02-09 US disclosed
US-4306014-A AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM RICOH CO., LTD. (JP) 1981-12-15 US disclosed
US-4201588-A NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, CARBAZIDES OR QUINONES AS PHOTOREDUCTANT; EXTERNAL HYDROGEN SOURCE EASTMAN KODAK COMPANY (US) 1980-05-06 US disclosed
US-4171221-A NONSILVER PHOTOGTAPHY EASTMAN KODAK COMPANY (US) 1979-10-16 US disclosed