SCHEMBL10446608

SCHEMBL10446608

CCCC1=C(CO)C(=O)c2ccccc2C1=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 1/20 0.42
FGFR2 P21802 1/20 0.42
FGFR4 P22455 1/20 0.42
FGFR3 P22607 1/20 0.42
DHODH Q02127 2/20 0.41
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
CDC25B P30305 4/20 0.41
MAPT P10636 7/20 0.40
ALDH1A1 P00352 7/20 0.40
LMNA P02545 6/20 0.40
SMN1; SMN2 Q16637 6/20 0.40
APAF1 O14727 4/20 0.40
HTT P42858 4/20 0.40
TDP1 Q9NUW8 4/20 0.40
PKM P14618 4/20 0.40
TDP2 O95551 3/20 0.40
KDM4E B2RXH2 3/20 0.40
L3MBTL1 Q9Y468 3/20 0.40
MITF O75030 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14307223 0.90 CDC25B (0.50) FGFR1FGFR2FGFR4FGFR3DHODH
SCHEMBL20375368 0.85 CDC25B (0.55) FGFR1FGFR2FGFR4FGFR3DHODH
SCHEMBL15764226 0.84 MEN1 (0.46) DHODHMEN1KMT2ACDC25BMAPT
SCHEMBL14307224 0.84 FGFR1 (0.49) FGFR1FGFR2FGFR4FGFR3DHODH
SCHEMBL9713924 0.81 APAF1 (0.56) FGFR1FGFR2FGFR4FGFR3DHODH
SCHEMBL31438079 0.81 DHODH (0.62) FGFR1FGFR2FGFR4FGFR3DHODH
SCHEMBL31611869 0.79 PTPN1 (0.46) FGFR1FGFR2FGFR4FGFR3DHODH
SCHEMBL571005 0.78 MAPT (0.53) MEN1KMT2ACDC25BMAPTALDH1A1
SCHEMBL15765912 0.77 MEN1 (0.50) DHODHMEN1KMT2ACDC25BMAPT
SCHEMBL9628338 0.77 MAPT (0.56) MEN1KMT2ACDC25BMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4324852-A REDOX COUPLES EASTMAN KODAK COMPANY (US) 1982-04-13 US claimed
US-4201588-A NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, CARBAZIDES OR QUINONES AS PHOTOREDUCTANT; EXTERNAL HYDROGEN SOURCE EASTMAN KODAK COMPANY (US) 1980-05-06 US claimed
US-4195998-A NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, QUINONE OR CARBAZIDE PHOTOREDUCTANT EASTMAN KODAK COMPANY (US) 1980-04-01 US claimed
EP-0383536-A2 Thermo-sensitive transfer printing medium SEIKO INSTRUMENTS INC. (JP) 1990-08-22 EP disclosed
US-4332884-A USING A DIOXIME CHELATING AGENT RICOH CO., LTD. (JP) 1982-06-01 US disclosed
US-4315068-A CONTAINING A COBALT-AMMINE COMPLEX AND A DIOXIME OR A BISIMIDAZOLIN-3-ONE CHELATING AGENT; STABILITY; COLOR DILMS RICOH CO., LTD. (JP) 1982-02-09 US disclosed
US-4306014-A AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM RICOH CO., LTD. (JP) 1981-12-15 US disclosed
US-4201588-A NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, CARBAZIDES OR QUINONES AS PHOTOREDUCTANT; EXTERNAL HYDROGEN SOURCE EASTMAN KODAK COMPANY (US) 1980-05-06 US disclosed
US-4171221-A NONSILVER PHOTOGTAPHY EASTMAN KODAK COMPANY (US) 1979-10-16 US disclosed