Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | APAF1 | O14727 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | S100A4 | P26447 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | TDP2 | O95551 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | TERT | O14746 | 1/20 | 0.48 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14307224 | 0.94 | FGFR1 (0.49) | CDC25BMEN1KMT2AMAPTLMNA | |
| SCHEMBL10446608 | 0.90 | FGFR1 (0.42) | CDC25BMEN1KMT2AMAPTLMNA | |
| SCHEMBL31611869 | 0.88 | PTPN1 (0.46) | MEN1KMT2AMAPTSMN1; SMN2APAF1 | |
| SCHEMBL571005 | 0.87 | MAPT (0.53) | CDC25BMEN1KMT2AMAPTLMNA | |
| SCHEMBL9628338 | 0.86 | MAPT (0.56) | CDC25BMEN1KMT2AMAPTLMNA | |
| SCHEMBL31438079 | 0.86 | DHODH (0.62) | CDC25BMEN1KMT2AMAPTLMNA | |
| SCHEMBL9713924 | 0.86 | APAF1 (0.56) | CDC25BMEN1KMT2AMAPTLMNA | |
| SCHEMBL9628124 | 0.84 | MAPT (0.61) | CDC25BMEN1KMT2AMAPTLMNA | |
| SCHEMBL9628126 | 0.82 | CDC25B (0.49) | CDC25BMEN1KMT2AMAPTLMNA | |
| SCHEMBL8258715 | 0.81 | CDC25B (0.46) | CDC25BMEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080020421-A1 | METHODS OF SCREENING AGENTS FOR CYTOTOXIC AND ANTIMICROBIAL ACTIVITY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-01-24 | — | — | US | disclosed |