Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | UBE2M | P61081 | 6/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 6/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10446869 | 0.92 | PPARG (0.43) | PPARGPPARDPPARAUBE2MDCUN1D1 | |
| SCHEMBL10446687 | 0.87 | UBE2M (0.48) | PPARGPPARDPPARAUBE2MDCUN1D1 | |
| SCHEMBL10447066 | 0.87 | PPARG (0.43) | PPARGPPARDPPARAUBE2MDCUN1D1 | |
| SCHEMBL10446688 | 0.85 | PPARG (0.41) | PPARGPPARDPPARAUBE2MDCUN1D1 | |
| SCHEMBL10446628 | 0.81 | UBE2M (0.49) | PPARGPPARDPPARAUBE2MDCUN1D1 | |
| SCHEMBL10446788 | 0.80 | UBE2M (0.44) | PPARGPPARDPPARAUBE2MDCUN1D1 | |
| SCHEMBL10446784 | 0.78 | RECQL (0.47) | PPARGPPARDPPARAUBE2MDCUN1D1 | |
| SCHEMBL10446424 | 0.78 | RAB9A (0.46) | PPARGPPARDPPARAUBE2MDCUN1D1 | |
| SCHEMBL10447044 | 0.77 | UBE2M (0.42) | PPARAUBE2MDCUN1D1THRBRAB9A | |
| SCHEMBL10447012 | 0.77 | HTT (0.39) | PPARGPPARDPPARAUBE2MDCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399422-A1 | Benzocycloalkane derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1990-11-28 | — | — | EP | disclosed |