Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | UBE2M | P61081 | 2/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.37 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10446688 | 0.93 | PPARG (0.41) | HTTPPARGPPARDPPARAPKM | |
| SCHEMBL10446676 | 0.90 | HTT (0.43) | HTTPPARGPPARDPPARAPKM | |
| SCHEMBL10446691 | 0.86 | RECQL (0.44) | HTTPPARGPPARDPPARAPKM | |
| SCHEMBL10446781 | 0.84 | UBE2M (0.47) | HTTPPARGPPARDPPARAPKM | |
| SCHEMBL10446779 | 0.84 | PKM (0.46) | HTTPPARGPPARDPPARAPKM | |
| SCHEMBL10446869 | 0.84 | PPARG (0.43) | HTTPPARGPPARDPPARAPKM | |
| SCHEMBL10447008 | 0.83 | UBE2M (0.46) | HTTPPARGPPARDPPARAPKM | |
| SCHEMBL10447041 | 0.83 | UBE2M (0.38) | HTTPPARGPPARDPPARAPKM | |
| SCHEMBL10446783 | 0.82 | RAB9A (0.44) | HTTPPARGPPARDPPARAPKM | |
| SCHEMBL10447047 | 0.82 | HTT (0.42) | HTTPPARGPPARDPPARAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399422-A1 | Benzocycloalkane derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1990-11-28 | — | — | EP | disclosed |