Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 7/20 | 0.51 |
| ▸ | DCUN1D1 | Q96GG9 | 7/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.44 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10446762 | 0.90 | UBE2M (0.52) | UBE2MDCUN1D1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10447033 | 0.89 | UBE2M (0.49) | UBE2MDCUN1D1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL9756708 | 0.85 | PKM (0.44) | UBE2MDCUN1D1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10446628 | 0.84 | UBE2M (0.49) | UBE2MDCUN1D1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10446648 | 0.84 | UBE2M (0.51) | UBE2MDCUN1D1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10446830 | 0.83 | MEN1 (0.52) | UBE2MDCUN1D1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10446687 | 0.83 | UBE2M (0.48) | UBE2MDCUN1D1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10447006 | 0.83 | UBE2M (0.46) | UBE2MDCUN1D1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10446599 | 0.82 | MEN1 (0.44) | UBE2MDCUN1D1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10447157 | 0.81 | NPSR1 (0.48) | UBE2MDCUN1D1TAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399422-A1 | Benzocycloalkane derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1990-11-28 | — | — | EP | disclosed |