Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | UBE2M | P61081 | 3/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10446779 | 0.88 | PKM (0.46) | PKMTAS1R3TAS1R1TAS1R2HTT | |
| SCHEMBL10447005 | 0.86 | MEN1 (0.52) | PKMTAS1R3TAS1R1TAS1R2HTT | |
| SCHEMBL10447056 | 0.85 | UBE2M (0.51) | TAS1R3TAS1R1TAS1R2HTTMAPT | |
| SCHEMBL10446781 | 0.84 | UBE2M (0.47) | PKMTAS1R3TAS1R1TAS1R2HTT | |
| SCHEMBL10447008 | 0.83 | UBE2M (0.46) | PKMTAS1R3TAS1R1TAS1R2HTT | |
| SCHEMBL10446676 | 0.82 | HTT (0.43) | PKMTAS1R3TAS1R1TAS1R2HTT | |
| SCHEMBL10447047 | 0.81 | HTT (0.42) | PKMTAS1R3TAS1R1TAS1R2HTT | |
| SCHEMBL10446762 | 0.81 | UBE2M (0.52) | PKMTAS1R3TAS1R1TAS1R2HTT | |
| SCHEMBL10447033 | 0.81 | UBE2M (0.49) | TAS1R3TAS1R1TAS1R2HTTUBE2M | |
| SCHEMBL10447156 | 0.81 | HTR2A (0.45) | HTTMAPTKMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3261755-A | — | — | None | — | — | JP | disclosed |
| JP-H03261755-A | BENZOCYCLOALKANE DERIVATIVE AND PRODUCTION AND DRUG THEREOF | TAKEDA CHEM IND LTD | 1991-11-21 | — | — | JP | disclosed |
| EP-0399422-A1 | Benzocycloalkane derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1990-11-28 | — | — | EP | disclosed |