Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | UBE2M | P61081 | 2/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10446758 | 0.95 | TAS1R3 (0.43) | PIN1RAB9AMEN1KMT2AATM | |
| SCHEMBL10446861 | 0.94 | PPARG (0.43) | PIN1RAB9AMEN1KMT2AATM | |
| SCHEMBL10446801 | 0.87 | RAB9A (0.46) | RAB9AMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL10446424 | 0.85 | RAB9A (0.46) | RAB9AMEN1KMT2AATMHTT | |
| SCHEMBL10447172 | 0.85 | RAB9A (0.41) | RAB9AMEN1KMT2AATMHTT | |
| SCHEMBL10447066 | 0.84 | PPARG (0.43) | PIN1RAB9AMEN1KMT2AATM | |
| SCHEMBL10446671 | 0.82 | P2RX3 (0.49) | RAB9AKMT2AHTTALDH1A1UBE2M | |
| SCHEMBL10446652 | 0.81 | P2RX3 (0.47) | RAB9AHTTALDH1A1UBE2MDCUN1D1 | |
| SCHEMBL10447157 | 0.78 | NPSR1 (0.48) | RAB9AMEN1KMT2AATMHTT | |
| SCHEMBL10446599 | 0.77 | MEN1 (0.44) | RAB9AMEN1KMT2AATMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399422-A1 | Benzocycloalkane derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1990-11-28 | — | — | EP | disclosed |