SCHEMBL10447305

SCHEMBL10447305

C=CC=C(C(=O)Br)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 1/20 0.47
AKR1C1 Q04828 1/20 0.42
ALDH1A1 P00352 4/20 0.39
CES1 P23141 4/20 0.39
CES2 O00748 3/20 0.39
TSHR P16473 2/20 0.39
DAO P14920 1/20 0.39
NAPRT Q6XQN6 1/20 0.39
MAPK1 P28482 3/20 0.39
TDP1 Q9NUW8 3/20 0.39
PTPN1 P18031 1/20 0.38
GSK3B P49841 1/20 0.38
MAPT P10636 3/20 0.37
KMT2A Q03164 3/20 0.37
LMNA P02545 3/20 0.37
HPGD P15428 3/20 0.37
POLB P06746 2/20 0.37
KDM4E B2RXH2 2/20 0.37
MEN1 O00255 2/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5348309 0.83 AKR1C1 (0.55) AKT1AKR1C1ALDH1A1CES1CES2
SCHEMBL3786208 0.83 AKR1C1 (0.55) AKT1AKR1C1ALDH1A1CES1CES2
SCHEMBL11402660 0.80 CES2 (0.48) AKT1AKR1C1ALDH1A1CES1CES2
SCHEMBL27909884 0.80 AKT1 (0.47) AKT1AKR1C1ALDH1A1CES1CES2
SCHEMBL11402663 0.80 CES2 (0.48) AKT1AKR1C1ALDH1A1CES1CES2
SCHEMBL4012690 0.76 TSHR (0.47) AKT1AKR1C1ALDH1A1CES1CES2
SCHEMBL9688036 0.76 AKT1 (0.42) AKT1AKR1C1ALDH1A1CES1CES2
SCHEMBL4012685 0.76 TSHR (0.47) AKT1AKR1C1ALDH1A1CES1CES2
SCHEMBL29435255 0.75 AKR1C1 (0.45) AKT1AKR1C1ALDH1A1CES1CES2
SCHEMBL2831280 0.74 AKT1 (0.43) AKT1ALDH1A1CES1CES2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0364785-A1 Thermosetting resin composition, printed circuit board using the resin composition and process for producing printed circuit board HITACHI, LTD. (JP) 1990-04-25 EP disclosed