Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.55 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CES1 | P23141 | 3/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3786208 | 1.00 | AKR1C1 (0.55) | AKR1C1AKT1KMT2AAKR1C2AKR1C3 | |
| SCHEMBL10943997 | 0.86 | AKR1C1 (0.50) | AKR1C1AKT1KMT2AAKR1C2AKR1C3 | |
| SCHEMBL27707062 | 0.86 | AKR1C1 (0.50) | AKR1C1AKT1KMT2AAKR1C2AKR1C3 | |
| SCHEMBL10818747 | 0.84 | AKR1C1 (0.48) | AKR1C1AKT1KMT2AAKR1C2AKR1C3 | |
| SCHEMBL11671992 | 0.84 | AKR1C1 (0.41) | AKR1C1AKT1KMT2AAKR1C2AKR1C3 | |
| SCHEMBL3293334 | 0.84 | KMO (0.53) | AKR1C1AKT1PTGS2 | |
| SCHEMBL11402660 | 0.83 | CES2 (0.48) | AKR1C1AKT1KMT2AAKR1C2AKR1C3 | |
| SCHEMBL11402663 | 0.83 | CES2 (0.48) | AKR1C1AKT1KMT2AAKR1C2AKR1C3 | |
| SCHEMBL27909884 | 0.83 | AKT1 (0.47) | AKR1C1AKT1KMT2AALDH1A1CES1 | |
| SCHEMBL10447305 | 0.83 | AKT1 (0.47) | AKR1C1AKT1KMT2AALDH1A1CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9077745-A | — | — | None | — | — | JP | disclosed |
| CN-116940897-A | Photosensitive resin composition and organic EL element partition wall | 株式会社力森诺科 | 2023-10-24 | — | — | CN | disclosed |
| CN-102532032-B | A kind of benzo nitrogen-containing heterocyclic compound, its preparation method, intermediate and application | KAIHUI TECHNOLOGY DEVELOPMENT (SHANGHAI) CO., LTD. (CN) | 2015-10-21 | — | — | CN | disclosed |
| CN-102532032-A | Benzo nitrogen-containing heterocyclic compound and preparation method, intermediate and application thereof | KAIHUI SCIENCE & TECHNOLOGY DEV SHANGHAI CO LTD | 2012-07-04 | — | — | CN | disclosed |
| US-20070254055-A1 | Therapeutic Avenanthramide Compounds | TRUSTEES OF TUFTS COLLEGE (US) | 2007-11-01 | — | — | US | disclosed |
| US-7186448-B2 | Composition and method for temporarily fixing solid | JSR CORPORATION (JP) | 2007-03-06 | — | — | US | disclosed |
| US-20060275939-A1 | Composition and method for temporarily fixing solids | JSR CORPORATION (JP) | 2006-12-07 | — | — | US | disclosed |
| US-20060100274-A1 | Therapeutic avenanthramide compounds | TRUSTEES OF TUFTS COLLEGE (US) | 2006-05-11 | — | — | US | disclosed |
| US-20050239892-A1 | Therapeutic avenathramide compounds | TRUSTEES OF TUFTS COLLEGE (US) | 2005-10-27 | — | — | US | disclosed |
| EP-1522567-A1 | COMPOSITION AND METHOD FOR TEMPORARILY FIXING SOLID | JSR Corporation (JP) | 2005-04-13 | — | — | EP | disclosed |
| US-4545984-A | TOPICAL TREATMENT OF OILY HAIR | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1985-10-08 | — | — | US | disclosed |
| EP-0071165-B1 | UNSATURATED ARYL KETONES AS ANTISEBORRHOEIC ADDITIVES FOR COSMETIC COMPOSITIONS | Henkel Kommanditgesellschaft auf Aktien (DE) | 1985-09-04 | — | — | EP | disclosed |
| US-4528286-A | Method of using certain aryl-mercapto-lower-alkanamides as antiseborrheic agents | HENKEL KOMMANDITGESELLSCHAFT (KGAA) (DE) | 1985-07-09 | — | — | US | disclosed |
| US-4503244-A | Sebosuppressive topical cosmetic preparations containing alkoxybenzoic acid esters, process for inhibiting sebum production and alkoxybenzoic acid esters | HENKEL KOMMANDITGESELLSCHAFT (DE) | 1985-03-05 | — | — | US | disclosed |
| US-4439418-A | UNSATURATED ARYL KETONE | HENKEL KGAA (DE) | 1984-03-27 | — | — | US | disclosed |
| EP-0079899-A1 | TOPICAL COSMETIC PREPARATIONS CONTAINING HETERO-ARYL-MERCAPTO-ALKANOIC ACID DERIVATIVES AS ADDITIVES HAVING AN ANTI-SEBORRHEA ACITIVITY. | HENKEL KGAA (DE) | 1983-06-01 | — | — | EP | disclosed |
| EP-0079913-A1 | ARENE-CARBOXYLIC ACID DERIVATIVES USED AS AGENTS HAVING AN ANTI-SEBORRHEA EFFECT CONTAINED IN COSMETIC COMPOSITIONS. | HENKEL KGAA (DE) | 1983-06-01 | — | — | EP | disclosed |
| EP-0071165-A1 | Unsaturated aryl ketones as antiseborrhoeic additives for cosmetic compositions | Henkel Kommanditgesellschaft auf Aktien (DE) | 1983-02-09 | — | — | EP | disclosed |
| WO-1982004391-A1 | DERIVATIVES OF ARYL AND HETERO-ARYL-MERCAPTO-ALKANOIC ACIDS AS ADDITIVES HAVING AN ANTI-SEBORRHEA ACTIVITY FOR COSMETIC PRODUCTS | MOELLER HINRICH | 1982-12-23 | — | — | WO | disclosed |
| WO-1982004189-A1 | ARENE-CARBOXYLIC ACID DERIVATIVES USED AS AGENTS HAVING AN ANTI-SEBORRHEA EFFECT CONTAINED IN COSMETIC COMPOSITIONS | MOELLER HINRICH | 1982-12-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239892-A1 | Therapeutic avenathramide compounds | VCAM1, ICAM1, OAT | AKR1C1 289/4885AKT1 1638/4885KMT2A 4502/4885 |
| US-20070254055-A1 | Therapeutic Avenanthramide Compounds | VCAM1, ICAM1, OAT | AKR1C1 224/4885AKT1 1380/4885KMT2A 4642/4885 |
| US-20060100274-A1 | Therapeutic avenanthramide compounds | VCAM1, ICAM1, OAT | AKR1C1 412/4885AKT1 1457/4885KMT2A 4603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.