SCHEMBL3786208

SCHEMBL3786208

C=CC=C(C(=O)O)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C1 Q04828 3/20 0.55
AKT1 P31749 1/20 0.50
KMT2A Q03164 5/20 0.46
AKR1C2 P52895 2/20 0.43
AKR1C3 P42330 2/20 0.43
ALDH1A1 P00352 4/20 0.42
CES1 P23141 3/20 0.42
CES2 O00748 2/20 0.42
TSHR P16473 2/20 0.42
DAO P14920 1/20 0.42
NAPRT Q6XQN6 1/20 0.42
PTGS2 P35354 1/20 0.42
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA9 Q16790 2/20 0.42
TDP1 Q9NUW8 3/20 0.41
MAPK1 P28482 3/20 0.41
MEN1 O00255 4/20 0.40
POLB P06746 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5348309 1.00 AKR1C1 (0.55) AKR1C1AKT1KMT2AAKR1C2AKR1C3
SCHEMBL10943997 0.86 AKR1C1 (0.50) AKR1C1AKT1KMT2AAKR1C2AKR1C3
SCHEMBL27707062 0.86 AKR1C1 (0.50) AKR1C1AKT1KMT2AAKR1C2AKR1C3
SCHEMBL10818747 0.84 AKR1C1 (0.48) AKR1C1AKT1KMT2AAKR1C2AKR1C3
SCHEMBL11671992 0.84 AKR1C1 (0.41) AKR1C1AKT1KMT2AAKR1C2AKR1C3
SCHEMBL3293334 0.84 KMO (0.53) AKR1C1AKT1PTGS2
SCHEMBL11402660 0.83 CES2 (0.48) AKR1C1AKT1KMT2AAKR1C2AKR1C3
SCHEMBL11402663 0.83 CES2 (0.48) AKR1C1AKT1KMT2AAKR1C2AKR1C3
SCHEMBL27909884 0.83 AKT1 (0.47) AKR1C1AKT1KMT2AALDH1A1CES1
SCHEMBL10447305 0.83 AKT1 (0.47) AKR1C1AKT1KMT2AALDH1A1CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104678462-B Silicone hydrogel lens with crosslinking hydrophilic coating 诺华股份有限公司 2019-11-05 CN claimed
JP-9077745-A None JP disclosed
CN-117042782-A Multilayer structure using chemically crosslinked alginic acid 持田制药株式会社 2023-11-10 CN disclosed
CN-116940897-A Photosensitive resin composition and organic EL element partition wall 株式会社力森诺科 2023-10-24 CN disclosed
WO-2023111170-A1 FUNCTIONALISED POLYSACCHARIDE RECKITT BENCKISER FINISH B.V. (NL) 2023-06-22 WO disclosed
CN-111918881-B Novel photocrosslinkable alginic acid derivative 持田制药株式会社 2022-08-12 CN disclosed
CN-111918881-A Novel photocrosslinkable alginic acid derivative 持田制药株式会社 2020-11-10 CN disclosed
EP-3169321-B1 PROPOLIS AND EXTRACTS THEREOF FOR THE TREATMENT OF SKIN CANCERS AND IMPROVEMENT OF SKIN HEALTH MANUKA HEALTH NEW ZEALAND LTD (NZ) 2020-07-15 EP disclosed
EP-2983681-B1 THERAPEUTIC COMPOSITIONS AND USES THEREOF MANUKA HEALTH NEW ZEALAND LTD (NZ) 2020-07-15 EP disclosed
CN-111094507-A Water-soluble pyrenetrisulfonic acid polymer and preparation method thereof 诺力昂化学品国际有限公司 2020-05-01 CN disclosed
US-5424164-A Image forming method FUJI PHOTO FILM CO., LTD (JP) 1995-06-13 US disclosed
US-5169660-A Steeping cereals in water to liquify endosperm, then macerating them in aqueous ethanol solution, separation and recovery of bran and endosperm materials HER MAJESTY THE QUEEN IN RIGHT OF CANADA, AS REPRESENTED BY THE MINISTER OF AGRICULTURE (CA) 1992-12-08 US disclosed
EP-0449557-A2 Recovery of values from cereal wastes Her Majesty in Right of Canada as represented by the Minister of Agriculture Canada (CA) 1991-10-02 EP disclosed
EP-0351856-A2 Thiazolo[5,4-b]azepine compounds Takeda Chemical Industries, Ltd. (JP) 1990-01-24 EP disclosed
US-4588671-A Photo and electron resist with donor-acceptor complex and light sensitive compound INSTITUT KHIMII AKADEMII NAUK SSSR (SU) 1986-05-13 US disclosed
US-4545984-A TOPICAL TREATMENT OF OILY HAIR HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1985-10-08 US disclosed
US-4528286-A Method of using certain aryl-mercapto-lower-alkanamides as antiseborrheic agents HENKEL KOMMANDITGESELLSCHAFT (KGAA) (DE) 1985-07-09 US disclosed
US-4503244-A Sebosuppressive topical cosmetic preparations containing alkoxybenzoic acid esters, process for inhibiting sebum production and alkoxybenzoic acid esters HENKEL KOMMANDITGESELLSCHAFT (DE) 1985-03-05 US disclosed
US-4439418-A UNSATURATED ARYL KETONE HENKEL KGAA (DE) 1984-03-27 US disclosed
US-4356298-A FROM ACID CHLORIDE OF 1,4-BIS-P-CARBOXYPHENYL-1,3-BUTADIENE, ISOPHTHALOYL CHLORIDE, 4,4-DIPHENOXYDIPHENYL SULFONE, DIPHENYL ETHER THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1982-10-26 US disclosed