SCHEMBL1044764

SCHEMBL1044764

COc1ccc(-c2nc(C(Br)(Br)Br)nc(C(Br)(Br)Br)n2)c2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.43
EP300 Q09472 1/20 0.42
KAT8 Q9H7Z6 1/20 0.42
NQO1 P15559 1/20 0.42
IMPDH2 P12268 1/20 0.40
IMPDH1 P20839 1/20 0.40
MAPT P10636 4/20 0.40
KMT2A Q03164 3/20 0.39
HPGD P15428 1/20 0.39
HPGDS O60760 1/20 0.39
LMNA P02545 3/20 0.38
HSD17B10 Q99714 3/20 0.38
ALDH1A1 P00352 2/20 0.38
CYP1A2 P05177 2/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2D6 P10635 2/20 0.38
TSHR P16473 2/20 0.38
USP2 O75604 2/20 0.38
ALOX15 P16050 2/20 0.38
TP53 P04637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29657689 1.00 IDO1 (0.43) IDO1EP300KAT8NQO1IMPDH2
SCHEMBL62367 0.86 IDO1 (0.42) IDO1EP300KAT8NQO1IMPDH2
SCHEMBL29350011 0.86 IDO1 (0.42) IDO1EP300KAT8NQO1IMPDH2
SCHEMBL544836 0.81 ALDH1A1 (0.49) HPGDLMNAHSD17B10ALDH1A1CYP1A2
SCHEMBL16117351 0.78 IDO1 (0.47) IDO1EP300KAT8NQO1IMPDH2
SCHEMBL15143913 0.78 IDO1 (0.38) IDO1EP300KAT8NQO1IMPDH2
SCHEMBL6031052 0.77 MAPT (0.48) IDO1EP300KAT8NQO1IMPDH2
SCHEMBL30416160 0.77 MAPT (0.48) IDO1EP300KAT8NQO1IMPDH2
SCHEMBL11406614 0.77 MAPT (0.48) IDO1EP300KAT8NQO1IMPDH2
SCHEMBL30620880 0.77 MAPT (0.48) IDO1EP300KAT8NQO1IMPDH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0621508-B1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO LTD (JP) 1996-09-25 EP claimed
US-5494777-A Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-02-27 US claimed
EP-0621508-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1994-10-26 EP claimed
US-11746255-B2 Hard-mask composition IRRESISTIBLE MATERIALS LTD (GB) 2023-09-05 US disclosed
US-10438808-B2 Hard-mask composition IRRESISTIBLE MATERIALS, LTD (GB) 2019-10-08 US disclosed
US-10290500-B2 Spin on hard mask material IRRESISTIBLE MATERIALS LTD (GB) 2019-05-14 US disclosed
US-20190127604-A1 HARD-MASK COMPOSITION NANO-C, INC. 2019-05-02 US disclosed
US-20170345669-A1 HARD-MASK COMPOSITION NANO-C, INC. 2017-11-30 US disclosed
US-20170278703-A1 Spin On Hard Mask Material IRRESISTIBLE MATERIALS LTD (GB) 2017-09-28 US disclosed
US-20150010703-A1 Spin on Hard-Mask Material THE UNIVERSITY OF BIRMINGHAM (GB) 2015-01-08 US disclosed
CN-104159956-A SPIN ON HARD-MASK MATERIAL UNIV BIRMINGHAM 2014-11-19 CN disclosed
US-6110641-A Radiation sensitive composition containing novel dye SHIPLEY COMPANY, L.L.C. (US) 2000-08-29 US disclosed
US-5910394-A RADIATION SENSITIVE CURED COATING WHICH EXHIBITS SUBSTANTIAL FLEXIBILITY AND REDUCES LINE GROWTH SHIPLEY COMPANY, L.L.C. (US) 1999-06-08 US disclosed
US-5866299-A BLEND OF ALKALI SOLUBLE RESIN AND PHOTOACID GENERATING COMPOUND SHIPLEY COMPANY, L.L.C. (US) 1999-02-02 US disclosed
EP-0621509-B1 Use of a radiation sensitive composition in the production of a liquid crystal display device JAPAN SYNTHETIC RUBBER CO LTD (JP) 1998-01-28 EP disclosed
US-5609988-A NEGATIVE RESIST, NOVOLAK, METHYLOL OR METHOXYMETHYL CURING AGENT, 2-BENZODIOXOLYL-4,6-BIS(TRICHLOROMETHYL)TRIAZINE ACID GENERATING AGENT JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-03-11 US disclosed
EP-0621508-B1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO LTD (JP) 1996-09-25 EP disclosed
US-5494777-A Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-02-27 US disclosed
EP-0621509-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1994-10-26 EP disclosed
EP-0621508-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1994-10-26 EP disclosed