Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 2/20 | 0.57 |
| ▸ | TUBB | P07437 | 2/20 | 0.57 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.57 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.57 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.57 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.57 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.57 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.57 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.57 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.57 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.57 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.57 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.57 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.57 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.57 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.56 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9874861 | 0.98 | TUBB4A (0.56) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9874857 | 0.89 | TUBB4A (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9826543 | 0.82 | MAPT (0.56) | PTPN1MAPTKDM4ELMNAPKM | |
| SCHEMBL3910841 | 0.79 | PTPN1 (0.53) | PTPN1MAPTKDM4EPTPRFALDH1A1 | |
| SCHEMBL3585269 | 0.79 | KDM4E (0.56) | PTPN1MAPTKDM4ELMNAPKM | |
| SCHEMBL17341863 | 0.77 | ALDH1A1 (0.44) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL25544955 | 0.76 | PTPN1 (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2157779 | 0.76 | TUBB4A (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4082306 | 0.75 | TUBB4A (0.66) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2044907 | 0.75 | IKBKB (0.77) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385043-A1 | New derivatives of 4-substituted piperazines | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (FAES) (ES) | 1990-09-05 | — | — | EP | claimed |
| EP-0343307-A1 | 4-Piperidinealkanamine derivatives | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (ES) | 1989-11-29 | — | — | EP | disclosed |