Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | HPGD | P15428 | 8/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.43 |
| ▸ | TUBB | P07437 | 2/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13713790 | 0.85 | TUBB4A (0.46) | ALDH1A1HPGDSMN1; SMN2TUBB4ATUBB | |
| SCHEMBL17343660 | 0.79 | ALDH1A1 (0.43) | ALDH1A1HPGDRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10447802 | 0.77 | TUBB4A (0.57) | ALDH1A1HPGDRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6812091 | 0.76 | MAPT (0.40) | ALDH1A1HPGDRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL114000 | 0.75 | HSD17B1 (0.47) | ALDH1A1HPGDRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL8325772 | 0.75 | ERN1 (0.43) | ALDH1A1HPGDRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9875040 | 0.75 | ALDH1A1 (0.40) | ALDH1A1HPGDRAB9ASMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL9874861 | 0.75 | TUBB4A (0.56) | ALDH1A1HPGDRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10205947 | 0.74 | PLA2G10 (0.49) | ALDH1A1HPGDRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL23449309 | 0.73 | ALDH1A1 (0.44) | ALDH1A1HPGDRAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154990-B1 | ROBUST PHOTOCHROMIC COMPOUNDS WITH SILICON- OR PHOSPHORUS-CONTAINING HETEROCYCLIC RING | UNIV HONG KONG (CN) | 2019-09-11 | — | — | EP | disclosed |
| US-9708528-B2 | Robust photochromic compounds with silicon- or phosphorus-containing heterocyclic ring and the production thereof | THE UNIVERSITY OF HONG KONG (HK) | 2017-07-18 | — | — | US | disclosed |
| WO-2015188790-A1 | ROBUST PHOTOCHROMIC COMPOUNDS WITH SILICON- OR PHOSPHORUS-CONTAINING HETEROCYCLIC RING AND PRODUCTION THEREOF | THE UNIVERSITY OF HONG KONG (CN) | 2015-12-17 | — | — | WO | disclosed |
| US-20150361332-A1 | ROBUST PHOTOCHROMIC COMPOUNDS WITH SILICON- OR PHOSPHORUS-CONTAINING HETEROCYCLIC RING AND THE PRODUCTION THEREOF | THE UNIVERSITY OF HONG KONG (HK) | 2015-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150361332-A1 | ROBUST PHOTOCHROMIC COMPOUNDS WITH SILICON- OR PHOSPHORUS-CONTAINING HETEROCYCLIC RING AND THE PRODUCTION THEREOF | CRY1, CRY2, P2RY10 | ALDH1A1 2747/4885HPGD 1853/4885RAB9A 2453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.