Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685456 | 0.86 | PPARD (0.40) | PPARDALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL9857513 | 0.82 | ALDH1A1 (0.32) | PPARDALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL10447621 | 0.78 | TSHR (0.40) | ALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL8839568 | 0.77 | PPARD (0.46) | PPARDALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL10439318 | 0.77 | TSHR (0.41) | PPARDALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL9685475 | 0.74 | PPARD (0.46) | PPARDALDH1A1LMNAHSD17B10TSHR | |
| Acetic Acid SCHEMBL29023251 | 0.71 | PPARD (0.58) | PPARDTSHR | |
| Butane SCHEMBL10448228 | 0.70 | — | — | |
| SCHEMBL248038 | 0.69 | PPARD (0.64) | PPARDTSHR | |
| SCHEMBL751991 | 0.68 | PPARD (0.54) | PPARDALDH1A1LMNAHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353955-A2 | Novel compounds | BEECHAM GROUP PLC (GB) | 1990-02-07 | — | — | EP | disclosed |