Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10447621 | 0.85 | TSHR (0.40) | ALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL10448229 | 0.82 | PPARD (0.38) | ALDH1A1LMNAHSD17B10TSHRPPARD | |
| SCHEMBL9685456 | 0.81 | PPARD (0.40) | ALDH1A1LMNAHSD17B10MAPTMAPK1 | |
| SCHEMBL10439318 | 0.78 | TSHR (0.41) | ALDH1A1LMNAHSD17B10TSHRPPARD | |
| SCHEMBL9857508 | 0.75 | POLB (0.38) | ALDH1A1MAPTMAPK1 | |
| SCHEMBL8839568 | 0.72 | PPARD (0.46) | ALDH1A1LMNAHSD17B10MAPTMAPK1 | |
| SCHEMBL12903591 | 0.72 | ALDH1A1 (0.52) | ALDH1A1LMNAHSD17B10MAPTMAPK1 | |
| SCHEMBL8764430 | 0.72 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10MAPTMAPK1 | |
| SCHEMBL8401424 | 0.72 | ALDH1A1 (0.59) | ALDH1A1LMNAHSD17B10MAPTMAPK1 | |
| SCHEMBL16463538 | 0.69 | ALDH1A1 (0.47) | ALDH1A1LMNAHSD17B10TSHRPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055458-A | PURINE DERIVATIVES HAVING ANTIVIRAL ACTIVITY | BEECHAM GROUP P.L.C. (GB) | 1991-10-08 | — | — | US | disclosed |
| EP-0353955-A2 | Novel compounds | BEECHAM GROUP PLC (GB) | 1990-02-07 | — | — | EP | disclosed |