Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9675367 | 0.85 | PPARD (0.37) | TSHRPPARDALDH1A1LMNAHSD17B10 | |
| SCHEMBL10448349 | 0.85 | TSHR (0.56) | TSHRPPARD | |
| SCHEMBL9685475 | 0.72 | PPARD (0.46) | TSHRPPARDALDH1A1LMNAHSD17B10 | |
| SCHEMBL9793358 | 0.71 | TSHR (0.46) | TSHRPPARDALDH1A1LMNAHSD17B10 | |
| Acetic Acid SCHEMBL28974626 | 0.68 | TSHR (0.75) | TSHRPPARDALDH1A1LMNAHSD17B10 | |
| SCHEMBL9675540 | 0.68 | PPARD (0.47) | TSHRPPARDMAPT | |
| SCHEMBL28821812 | 0.67 | TSHR (0.65) | TSHRPPARDALDH1A1LMNAHSD17B10 | |
| SCHEMBL10439318 | 0.67 | TSHR (0.41) | TSHRPPARDALDH1A1LMNAHSD17B10 | |
| SCHEMBL4971866 | 0.66 | TSHR (0.71) | TSHRPPARD | |
| SCHEMBL10485634 | 0.66 | TSHR (0.58) | TSHRPPARDLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399743-A1 | Phosphonomethylthio-alkoseypureine derivatives, intermediate products for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1990-11-28 | — | — | EP | disclosed |