Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.41 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3706925 | 1.00 | QPCT (0.43) | QPCTALDH1A1TBXAS1L3MBTL1POLB | |
| SCHEMBL3668830 | 0.84 | QPCT (0.49) | QPCTSMN1; SMN2KMT2A | |
| SCHEMBL14271650 | 0.83 | ALDH1A1 (0.50) | QPCTALDH1A1TBXAS1L3MBTL1POLB | |
| SCHEMBL13609286 | 0.82 | GAA (0.52) | QPCTALDH1A1L3MBTL1SMN1; SMN2EGLN3 | |
| SCHEMBL10311722 | 0.82 | QPCT (0.50) | QPCTALDH1A1TBXAS1L3MBTL1POLB | |
| SCHEMBL3664283 | 0.77 | QPCT (0.60) | QPCTSMN1; SMN2KMT2A | |
| SCHEMBL3662446 | 0.77 | QPCT (0.60) | QPCTSMN1; SMN2KMT2A | |
| SCHEMBL10448592 | 0.76 | AGTR2 (0.43) | QPCTALDH1A1TBXAS1L3MBTL1POLB | |
| SCHEMBL26305930 | 0.76 | ALDH1A1 (0.45) | QPCTALDH1A1TBXAS1L3MBTL1SMN1; SMN2 | |
| SCHEMBL3699910 | 0.75 | ALDH1A1 (0.40) | ALDH1A1POLBLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386611-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1990-09-12 | — | — | EP | disclosed |