Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 2/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.42 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.41 |
| ▸ | QPCT | Q16769 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10448593 | 0.76 | QPCT (0.43) | TBXAS1EGLN3QPCTALDH1A1LMNA | |
| SCHEMBL3706925 | 0.76 | QPCT (0.43) | TBXAS1EGLN3QPCTALDH1A1LMNA | |
| SCHEMBL19091362 | 0.75 | TBXAS1 (0.47) | TBXAS1EGLN3QPCTALDH1A1 | |
| SCHEMBL7609694 | 0.74 | QPCT (0.50) | TBXAS1EGLN3QPCTALDH1A1L3MBTL1 | |
| SCHEMBL20987982 | 0.74 | TBXAS1 (0.49) | TBXAS1EGLN3QPCTALDH1A1LMNA | |
| SCHEMBL10447987 | 0.73 | CTSS (0.48) | AGTR2QPCTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL278416 | 0.73 | QPCT (0.53) | TBXAS1EGLN3QPCTALDH1A1 | |
| SCHEMBL14271650 | 0.72 | ALDH1A1 (0.50) | TBXAS1EGLN3QPCTALDH1A1LMNA | |
| SCHEMBL5766577 | 0.71 | QPCT (0.48) | TBXAS1EGLN3QPCTALDH1A1L3MBTL1 | |
| SCHEMBL27787847 | 0.71 | TBXAS1 (0.57) | TBXAS1EGLN3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386611-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1990-09-12 | — | — | EP | disclosed |