Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 12/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 11/20 | 0.42 |
| ▸ | MME | P08473 | 2/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 6/20 | 0.41 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10448895 | 0.88 | PTGS2 (0.44) | PPARGPPARAKDM4ELMNACYP1A2 | |
| SCHEMBL10448900 | 0.87 | BACE1 (0.43) | PPARGPPARAKDM4EPKMPOLB | |
| SCHEMBL10448750 | 0.82 | BRS3 (0.44) | PPARGPPARA | |
| SCHEMBL8156103 | 0.81 | HSD17B10 (0.49) | PPARGPPARALMNAHSD17B10POLB | |
| SCHEMBL10448896 | 0.79 | BACE1 (0.41) | PPARGPPARAKDM4EPKM | |
| Bicarbonate SCHEMBL28004213 | 0.77 | NPC1 (0.47) | PPARGPPARALMNACYP1A2PKM | |
| SCHEMBL8148623 | 0.75 | MAPT (0.46) | PPARGPPARALMNAKMT2A | |
| SCHEMBL237801 | 0.75 | PPARA (0.49) | PPARGPPARAITGA4ITGB1MME | |
| SCHEMBL3728321 | 0.75 | KDM4E (0.58) | KDM4ELMNACYP1A2CYP2C9HSD17B10 | |
| SCHEMBL7795580 | 0.74 | PTGS2 (0.48) | KDM4ELMNACYP1A2CYP2C9HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0360622-A2 | Novel optically active benzene derivatives, process for producing the same and liquid-crystalline composition containing said derivatives as liquid-crystalline compound and light switching elements | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-03-28 | — | — | EP | disclosed |