Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | CFD | P00746 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10448896 | 0.90 | BACE1 (0.41) | BACE1CYP4F2CYP4A11ADORA3ADORA2A | |
| SCHEMBL10448899 | 0.87 | PPARG (0.43) | KDM4EPKMPOLBKMT2APPARG | |
| SCHEMBL10448751 | 0.83 | FOLH1 (0.44) | BACE1PPARGPPARA | |
| SCHEMBL10448895 | 0.78 | PTGS2 (0.44) | KDM4EPKMKMT2APPARGPPARA | |
| SCHEMBL11835597 | 0.77 | BACE1 (0.44) | BACE1CYP4F2CYP4A11ADORA3ADORA2A | |
| SCHEMBL27489237 | 0.77 | BACE1 (0.51) | BACE1CYP4F2CYP4A11ADORA3ADORA2A | |
| SCHEMBL28035132 | 0.77 | BACE1 (0.51) | BACE1CYP4F2CYP4A11ADORA3ADORA2A | |
| SCHEMBL9127323 | 0.75 | CA12 (0.44) | KDM4EPOLBKMT2A | |
| SCHEMBL8156103 | 0.75 | HSD17B10 (0.49) | POLBKMT2APPARGPPARA | |
| SCHEMBL27368090 | 0.75 | BACE1 (0.49) | BACE1CYP4F2CYP4A11ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0360622-A2 | Novel optically active benzene derivatives, process for producing the same and liquid-crystalline composition containing said derivatives as liquid-crystalline compound and light switching elements | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-03-28 | — | — | EP | disclosed |