Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 4/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | YAP1 | P46937 | 1/20 | 0.45 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | VEGFA | P15692 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10003780 | 0.82 | RAPGEF4 (0.51) | RAPGEF4CA1CA2CYP2C9RECQL | |
| Hydrochloric Acid SCHEMBL15974393 | 0.82 | RAPGEF4 (0.51) | RAPGEF4CA1CA2CYP2C9RECQL | |
| SCHEMBL16540512 | 0.82 | RAPGEF4 (0.56) | RAPGEF4CA1CA2CYP2C9RECQL | |
| SCHEMBL14005234 | 0.82 | RAPGEF4 (0.56) | RAPGEF4CA1CA2CYP2C9RECQL | |
| SCHEMBL15974465 | 0.80 | RAPGEF4 (0.49) | RAPGEF4CA1CA2CYP2C9RECQL | |
| SCHEMBL10003744 | 0.79 | NOD2 (0.57) | RAPGEF4CA1CA2CYP2C9L3MBTL1 | |
| SCHEMBL16539947 | 0.78 | RAPGEF4 (0.52) | RAPGEF4CA1CA2CYP2C9RECQL | |
| SCHEMBL26054490 | 0.78 | RAPGEF4 (0.52) | RAPGEF4CA1CA2CYP2C9RECQL | |
| SCHEMBL5534938 | 0.76 | RAPGEF4 (0.74) | RAPGEF4CA1CA2L3MBTL1KMT2A | |
| SCHEMBL15974712 | 0.75 | RAPGEF4 (0.43) | RAPGEF4CA1CA2CYP2C9RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0396937-A2 | 3-Substituted polypyrrole | NIPPON OIL CO. LTD. (JP) | 1990-11-14 | — | — | EP | disclosed |