Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16540512 | 0.87 | RAPGEF4 (0.56) | RAPGEF4CA1CA2L3MBTL1CYP2C9 | |
| SCHEMBL1365701 | 0.87 | PKM (0.51) | RAPGEF4L3MBTL1HTTALDH1A1HPGD | |
| SCHEMBL26054490 | 0.83 | RAPGEF4 (0.52) | RAPGEF4CA1CA2L3MBTL1CYP2C9 | |
| SCHEMBL16539947 | 0.83 | RAPGEF4 (0.52) | RAPGEF4CA1CA2L3MBTL1CYP2C9 | |
| SCHEMBL10448997 | 0.82 | RAPGEF4 (0.55) | RAPGEF4CA1CA2L3MBTL1CYP2C9 | |
| SCHEMBL10003744 | 0.81 | NOD2 (0.57) | RAPGEF4CA1CA2L3MBTL1CYP2C9 | |
| SCHEMBL2718306 | 0.79 | LMNA (0.49) | RAPGEF4CA1CA2CYP2C9ALDH1A1 | |
| Hydrochloric Acid SCHEMBL15974393 | 0.79 | RAPGEF4 (0.51) | RAPGEF4CA1CA2L3MBTL1CYP2C9 | |
| SCHEMBL10003780 | 0.79 | RAPGEF4 (0.51) | RAPGEF4CA1CA2L3MBTL1CYP2C9 | |
| SCHEMBL3834757 | 0.78 | RAPGEF4 (0.65) | RAPGEF4CA1CA2L3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7446186-B2 | Pyrroles substituted by oligonucleotides | BIOMERIEUX (FR) | 2008-11-04 | — | — | US | disclosed |
| US-7446186-B2 | Pyrroles substituted by oligonucleotides | BIOMERIEUX (FR) | 2008-11-04 | — | — | US | disclosed |