SCHEMBL1044902

SCHEMBL1044902

C1=CC(=C(c2ccc3ccccc3c2)c2ccc3ccccc3c2)C=C1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
F2 P00734 1/20 0.48
PLG P00747 1/20 0.48
PLAU P00749 1/20 0.48
KLKB1 P03952 1/20 0.48
KLK1 P06870 1/20 0.48
PRSS1 P07477 1/20 0.48
SMN1; SMN2 Q16637 3/20 0.44
KDM4E B2RXH2 2/20 0.44
HPGD P15428 2/20 0.44
ALDH1A1 P00352 2/20 0.44
MEN1 O00255 1/20 0.44
EGFR P00533 1/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
MAPT P10636 1/20 0.44
PKM P14618 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17288830 0.73 CES2 (0.60) CES2CES1F2PLGPLAU
SCHEMBL2837486 0.72 CES2 (0.65) CES2CES1F2PLGPLAU
SCHEMBL647841 0.72 TDP1 (0.40) CES2CES1F2SMN1; SMN2KDM4E
SCHEMBL4954203 0.72 CES2 (0.44) CES2CES1F2PLGPLAU
SCHEMBL30380669 0.70 CES2 (0.56) CES2CES1F2PLGPLAU
SCHEMBL3553076 0.70 CES2 (0.56) CES2CES1F2PLGPLAU
SCHEMBL14322691 0.70 CES2 (0.56) CES2CES1F2PLGPLAU
SCHEMBL31749366 0.70 CES2 (0.56) CES2CES1F2PLGPLAU
SCHEMBL8344284 0.70 CES2 (0.68) CES2CES1F2PLGPLAU
SCHEMBL1045207 0.70 SMN1; SMN2 (0.45) SMN1; SMN2KDM4EHPGDALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2275451-B1 Method for producing propylene-based copolymer MITSUI CHEMICALS INC (JP) 2016-10-19 EP disclosed
US-20160280819-A1 CATALYST FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING OLEFIN POLYMER, METHOD FOR PRODUCING PROPYLENE-BASED COPOLYMER, PROPYLENE POLYMER, PROPYLENE-BASED POLYMER COMPOSITION, AND USE OF THOSE MITSUI CHEMICALS, INC. (JP) 2016-09-29 US disclosed
US-9382356-B2 Catalyst for olefin polymerization, method for producing olefin polymer, method for producing propylene-based copolymer, propylene polymer, propylene-based polymer composition, and use of those MITSUI CHEMICALS, INC. (JP) 2016-07-05 US disclosed
EP-2275451-A2 Method for producing propylene-based copolymer Mitsui Chemicals, Inc. (JP) 2011-01-19 EP disclosed
US-20080220193-A1 Catalyst for olefin polymerization, method for producing olefin polymer, method for producing propylene-based copolymer, propylene polymer, propylene-based polymer composition, and use of those MITSUI CHEMICALS, INC. 2008-09-11 US disclosed
EP-1900758-A1 CATALYST FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING OLEFIN POLYMER, METHOD FOR PRODUCING PROPYLENE COPOLYMER, PROPYLENE POLYMER, PROPYLENE POLYMER COMPOSITION, AND USE OF THOSE Mitsui Chemicals, Inc. (JP) 2008-03-19 EP disclosed