SCHEMBL647841

SCHEMBL647841

C1=CC(=C(c2ccccc2)c2ccccc2)C=C1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 0.40
HDAC6 Q9UBN7 1/20 0.40
CES2 O00748 3/20 0.39
CES1 P23141 3/20 0.39
TSHR P16473 3/20 0.39
ALDH1A1 P00352 3/20 0.39
DAO P14920 1/20 0.39
NAPRT Q6XQN6 1/20 0.39
CYP3A4 P08684 5/20 0.38
HPGD P15428 4/20 0.38
SMN1; SMN2 Q16637 4/20 0.38
MAPT P10636 3/20 0.38
MEN1 O00255 2/20 0.38
TP53 P04637 2/20 0.38
ALOX15 P16050 2/20 0.38
KMT2A Q03164 2/20 0.38
KDM4E B2RXH2 1/20 0.38
NPC1 O15118 1/20 0.38
MITF O75030 1/20 0.38
NFKB1 P19838 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28719659 0.89 TDP1 (0.35) TDP1HDAC6CES2CES1TSHR
SCHEMBL11327650 0.89 CES2 (0.54) TDP1HDAC6CES2CES1TSHR
SCHEMBL11330207 0.87 NPC1 (0.40) TDP1HDAC6CES2CES1CYP3A4
SCHEMBL1045207 0.85 SMN1; SMN2 (0.45) TDP1ALDH1A1CYP3A4HPGDSMN1; SMN2
SCHEMBL28580453 0.85 HDAC1 (0.43) TDP1HDAC6CES2CES1NPC1
SCHEMBL1042527 0.83 PARP1 (0.46) TSHRALDH1A1MAPTMEN1ALOX15
SCHEMBL24220764 0.80 PKM (0.53) ALDH1A1CYP3A4MAPTMEN1TP53
SCHEMBL8739454 0.77 CYP3A4 (0.63) TDP1HDAC6CES2CES1TSHR
SCHEMBL31382802 0.77 TDP1 (0.37) TDP1HDAC6CES2CES1TSHR
SCHEMBL401165 0.76 CES2 (0.46) TDP1CES2CES1TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 455 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120020156-A Ethylene copolymer and preparation method and application thereof 中国石油天然气股份有限公司 2025-05-20 CN claimed
EP-4538307-A1 POLYOLEFIN ELASTOMER AND USE THEREOF IN PHOTOVOLTAIC ENCAPSULATION FILM Wanhua Chemical Group Co., Ltd. (CN) 2025-04-16 EP claimed
WO-2025043950-A1 POLYOLEFIN ELASTOMER AND USE THEREOF IN PHOTOVOLTAIC ENCAPSULATION FILM 万华化学集团股份有限公司 2025-03-06 WO claimed
CN-118384522-B Device and method for preparing POE elastomer 广东众和工程设计有限公司 2024-12-06 CN claimed
CN-118384522-A Device and method for preparing POE elastomer 广东众和工程设计有限公司 2024-07-26 CN claimed
CN-118063697-B Process for preparing cycloolefin-ethylene copolymers 辽宁鲁华泓锦新材料科技有限公司 2024-06-21 CN claimed
CN-118063697-A Process for preparing cycloolefin-ethylene copolymers 辽宁鲁华泓锦新材料科技有限公司 2024-05-24 CN claimed
US-11932813-B2 Electrochromic materials; preparation and use thereof UNIVERSITY OF CONNECTICUT (US) 2024-03-19 US claimed
CN-113302237-B Propylene polymer composition 住友化学株式会社 2024-01-19 CN claimed
CN-117106118-A Poly alpha-olefin pour point depressant and preparation method thereof 中国石油天然气股份有限公司 2023-11-24 CN claimed
WO-2002071466-A1 METAL PATTERN FORMATION ATOTECH DEUTSCHLAND GMBH (DE) 2002-09-12 WO claimed
US-6214762-B1 REACTION OF METAL FULVENE COMPLEX AND UNSATURATED COMPOUND INSERTION COMPLEXES AND THE USE THEREOF AS CATALYSTS FOR THE POLYMERIZATION OF OLEFINS AND/OR DIENES AND AS HYDROGENATION CATALYSTS. BAYER AKTIENGESELLSCHAFT (DE) 2001-04-10 US claimed
EP-0914392-B1 LUMINESCING INKS AND USE OF SUCH INKS IN CODING AND OTHER MARKING OPERATIONS POST OFFICE (GB) 2000-10-25 EP claimed
EP-0980872-A2 Catalysts based upon fulvene-metal complexes Bayer Aktiengesellschaft (DE) 2000-02-23 EP claimed
US-5663030-A A PHENYL OR NORBORNANE DERIVATIVE AS AN ADDITIVE TO REDUCE HEAT AND ENERGY REQUIRED TO FUSE THE TONER AND TO REDUCE JAMMING OF THE EQUIPMENT XEROX CORPORATION (US) 1997-09-02 US claimed
US-5554795-A Process for preparing cyclopentadienyl-type ligands PHILLIPS PETROLEUM COMPANY (US) 1996-09-10 US claimed
US-4786689-A Process for metallating nonconjugated diene-containing ethylene polymers and graft polymers prepared therefrom THE DOW CHEMICAL COMPANY (US) 1988-11-22 US claimed
US-4452299-A POURING FLUVENES AND POLYMERIZABLE MATERIALS INTO MOLDS; CURING ASHLAND OIL, INC. (US) 1984-06-05 US claimed
US-4394466-A AGGREGATES, METAL CARBOXYLATE CATALYST ASHLAND OIL, INC. (US) 1983-07-19 US claimed
US-4320218-A CURABLE FULRENES AND A METAL SALT CATALYST ASHLAND OIL, INC. (US) 1982-03-16 US claimed