SCHEMBL1045207

SCHEMBL1045207

C1=CC(=C(c2ccc(-c3ccccc3)cc2)c2ccc(-c3ccccc3)cc2)C=C1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.45
MAPT P10636 4/20 0.45
WDR5 P61964 1/20 0.45
CYP1A2 P05177 2/20 0.42
MMP3 P08254 1/20 0.42
BCL2L1 Q07817 1/20 0.42
RAB9A P51151 4/20 0.42
NPC1 O15118 2/20 0.42
CTDSP1 Q9GZU7 1/20 0.42
ALDH1A1 P00352 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
PTPN1 P18031 1/20 0.41
GSK3B P49841 1/20 0.41
LMNA P02545 2/20 0.39
CDC25B P30305 1/20 0.39
ATM Q13315 1/20 0.39
FFAR1 O14842 1/20 0.39
HIF1A Q16665 1/20 0.39
HPGD P15428 3/20 0.38
ERCC5 P28715 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL647841 0.85 TDP1 (0.40) SMN1; SMN2MAPTCYP1A2RAB9ANPC1
SCHEMBL11327650 0.80 CES2 (0.54) MAPTCYP1A2L3MBTL1ATMHPGD
SCHEMBL28580453 0.77 HDAC1 (0.43) RAB9ANPC1FFAR1TDP1
SCHEMBL28719659 0.76 TDP1 (0.35) SMN1; SMN2MAPTCYP1A2RAB9ANPC1
SCHEMBL1040818 0.75 KIF11 (0.50) PTPN1GSK3BCA1CA2
SCHEMBL24220764 0.72 PKM (0.53) MAPTCYP1A2RAB9ANPC1ALDH1A1
SCHEMBL29712521 0.71 CES2 (0.44) SMN1; SMN2MAPTRAB9ANPC1ALDH1A1
SCHEMBL2873871 0.71 ALDH1A1 (0.44) SMN1; SMN2MAPTRAB9ANPC1ALDH1A1
SCHEMBL17995167 0.71 CES2 (0.44) SMN1; SMN2MAPTBCL2L1RAB9ANPC1
SCHEMBL29712522 0.71 CES2 (0.44) SMN1; SMN2MAPTRAB9ANPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2275451-B1 Method for producing propylene-based copolymer MITSUI CHEMICALS INC (JP) 2016-10-19 EP disclosed
US-20160280819-A1 CATALYST FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING OLEFIN POLYMER, METHOD FOR PRODUCING PROPYLENE-BASED COPOLYMER, PROPYLENE POLYMER, PROPYLENE-BASED POLYMER COMPOSITION, AND USE OF THOSE MITSUI CHEMICALS, INC. (JP) 2016-09-29 US disclosed
US-9382356-B2 Catalyst for olefin polymerization, method for producing olefin polymer, method for producing propylene-based copolymer, propylene polymer, propylene-based polymer composition, and use of those MITSUI CHEMICALS, INC. (JP) 2016-07-05 US disclosed
EP-2275451-A2 Method for producing propylene-based copolymer Mitsui Chemicals, Inc. (JP) 2011-01-19 EP disclosed
US-20080220193-A1 Catalyst for olefin polymerization, method for producing olefin polymer, method for producing propylene-based copolymer, propylene polymer, propylene-based polymer composition, and use of those MITSUI CHEMICALS, INC. 2008-09-11 US disclosed
EP-1900758-A1 CATALYST FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING OLEFIN POLYMER, METHOD FOR PRODUCING PROPYLENE COPOLYMER, PROPYLENE POLYMER, PROPYLENE POLYMER COMPOSITION, AND USE OF THOSE Mitsui Chemicals, Inc. (JP) 2008-03-19 EP disclosed