Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 6/20 | 0.65 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.65 |
| ▸ | BCR | P11274 | 6/20 | 0.65 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.58 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP4B1 | P13584 | 2/20 | 0.58 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.58 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.58 |
| ▸ | CYP2A7 | P20853 | 2/20 | 0.58 |
| ▸ | CYP3A7 | P24462 | 2/20 | 0.58 |
| ▸ | CYP2F1 | P24903 | 2/20 | 0.58 |
| ▸ | CYP2C18 | P33260 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10049229 | 0.95 | ABL1 (0.61) | ABL1ABCB1BCRCYP1A1CYP1B1 | |
| SCHEMBL21589900 | 0.86 | ABL1 (0.50) | ABL1ABCB1BCRCYP1A1CYP1B1 | |
| SCHEMBL2274524 | 0.85 | ABL1 (0.79) | ABL1ABCB1BCRCYP1A1CYP1B1 | |
| SCHEMBL12770829 | 0.85 | ACHE (0.56) | ABL1ABCB1BCRACHEALDH1A1 | |
| Water SCHEMBL27689515 | 0.83 | ABL1 (0.76) | ABL1ABCB1BCRCYP1A1CYP1B1 | |
| Ethane SCHEMBL27670651 | 0.83 | ABL1 (0.76) | ABL1ABCB1BCRCYP1A1CYP1B1 | |
| SCHEMBL3676881 | 0.82 | ACHE (0.83) | ABL1ABCB1BCRACHENPC1 | |
| SCHEMBL12714843 | 0.82 | ACHE (0.83) | ABL1ABCB1BCRACHENPC1 | |
| SCHEMBL295716 | 0.82 | ACHE (0.83) | ABL1ABCB1BCRACHENPC1 | |
| SCHEMBL25485549 | 0.82 | ACHE (0.65) | ABL1ABCB1BCRACHEHSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150224099-A1 | ANTITUBERCULOUS COMPOSITION COMPRISING OXAZOLE COMPOUNDS | OTSUKA PHARMA CO LTD (JP) | 2015-08-13 | — | — | US | disclosed |
| US-8987304-B2 | Antituberculous composition comprising oxazole compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2015-03-24 | — | — | US | disclosed |
| US-8530689-B2 | Processes for the preparation of biphenyl compounds | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2013-09-10 | — | — | US | disclosed |
| US-20120135997-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A LACTAM OR BENZENESULFONAMIDE COMPOUND | SHIONOGI & CO., LTD. (JP) | 2012-05-31 | — | — | US | disclosed |
| US-20110207957-A1 | PROCESSES FOR THE PREPARATION OF BIPHENYL COMPOUNDS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2011-08-25 | — | — | US | disclosed |
| EP-2269694-A2 | Antituberculous composition comprising oxazole compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2011-01-05 | — | — | EP | disclosed |
| US-20090275528-A1 | ANTITUBERCULOUS COMPOSITION COMPRISING OXAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2009-11-05 | — | — | US | disclosed |
| US-6686495-B2 | IN PRESENCE OF PALLADIUM CATALYST; USEFUL IN PRODUCING CHEMICAL INTERMEDIATES FOR PHARMACEUTICALS, OPTICAL BRIGHTENING AGENTS AND AGROCHEMICALS | OMG AG & CO KG (DE) | 2004-02-03 | — | — | US | disclosed |
| US-20020107426-A1 | Process for the preparation of mono-, bi- or poly- functional biaryls | UMICORE AG & CO. KG (DE) | 2002-08-08 | — | — | US | disclosed |
| EP-1199292-A1 | Process for the production of mono-, bi- or polyfunctional biaryls | OMG AG & Co. KG (DE) | 2002-04-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150224099-A1 | ANTITUBERCULOUS COMPOSITION COMPRISING OXAZOLE COMPOUNDS | OXA1L, ARG1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | ABL1 1497/4885ABCB1 126/4885BCR 2703/4885 |
| US-20120135997-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A LACTAM OR BENZENESULFONAMIDE COMPOUND | BACE1, STS, APP | ABL1 2940/4885ABCB1 121/4885BCR 306/4885 |
| US-20090275528-A1 | ANTITUBERCULOUS COMPOSITION COMPRISING OXAZOLE COMPOUNDS | OXA1L, ARG1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | ABL1 1497/4885ABCB1 126/4885BCR 2703/4885 |
| US-20110207957-A1 | PROCESSES FOR THE PREPARATION OF BIPHENYL COMPOUNDS | C1S, BAX, C9 | ABL1 1454/4885ABCB1 1237/4885BCR 124/4885 |
| US-20020107426-A1 | Process for the preparation of mono-, bi- or poly- functional biaryls | CYP4F3, CYP4F2, CYP2F1 | ABL1 538/4885ABCB1 766/4885BCR 2181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.