SCHEMBL295716

SCHEMBL295716

COc1ccc(-c2ccc(C)cc2)cc1

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.83
NPC1 O15118 3/20 0.63
RAB9A P51151 3/20 0.63
KMT2A Q03164 1/20 0.63
RELA Q04206 1/20 0.62
CA12 O43570 1/20 0.61
CA1 P00915 1/20 0.61
CA2 P00918 1/20 0.61
CA7 P43166 1/20 0.61
CA9 Q16790 1/20 0.61
CA14 Q9ULX7 1/20 0.61
ESR2 Q92731 1/20 0.61
SMN1; SMN2 Q16637 2/20 0.55
MAPT P10636 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
TP53 P04637 1/20 0.54
MAPK1 P28482 1/20 0.54
CASP3 P42574 1/20 0.54
SENP8 Q96LD8 1/20 0.54
SENP7 Q9BQF6 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12714843 1.00 ACHE (0.83) ACHENPC1RAB9AKMT2ARELA
SCHEMBL3676881 1.00 ACHE (0.83) ACHENPC1RAB9AKMT2ARELA
Hydrazine SCHEMBL27971879 0.95 ACHE (0.75) ACHENPC1RAB9AKMT2ARELA
SCHEMBL12276818 0.93 ACHE (0.71) ACHENPC1RAB9AKMT2ARELA
SCHEMBL12334794 0.93 ACHE (0.71) ACHENPC1RAB9AKMT2ARELA
SCHEMBL12761860 0.93 ACHE (0.71) ACHENPC1RAB9AKMT2ARELA
SCHEMBL12770835 0.93 ACHE (0.71) ACHENPC1RAB9AKMT2ARELA
SCHEMBL12335539 0.93 ACHE (0.71) ACHENPC1RAB9AKMT2ARELA
SCHEMBL18708707 0.93 ACHE (0.71) ACHENPC1RAB9AKMT2ARELA
SCHEMBL14826485 0.93 ACHE (0.71) ACHENPC1RAB9AKMT2ARELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 525 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118594607-A Preparation method and application of heterogeneous gamma-alumina-ionic liquid-palladium catalyst 河北工业大学 2024-09-06 CN claimed
CN-104130175-A Different-position substituted indolone derivatives and application thereof UNIV TIANJIN SCIENCE & TECH 2014-11-05 CN claimed
CN-119191946-B Electrophilic cross-coupling method of aryl perfluoro butyl sulfonate and aryl bromide 南京工业大学 2026-05-15 CN disclosed
US-12510529-B2 Method for determining authenticity and adulteration of marked petroleum hydrocarbons SICPA HOLDING SA (CH) 2025-12-30 US disclosed
CN-119191946-A Electrophilic cross-coupling method of aryl perfluoro butyl sulfonate and aryl bromide 南京工业大学 2024-12-27 CN disclosed
CN-118834121-A Method for preparing biaryl compound by cross-coupling of diazonium salt and aryl bromide under nickel catalysis 浙江工业大学 2024-10-25 CN disclosed
CN-118594607-A Preparation method and application of heterogeneous gamma-alumina-ionic liquid-palladium catalyst 河北工业大学 2024-09-06 CN disclosed
CN-117986097-B Novel method for Suzuki coupling based on photocatalysis 科莱博(江苏)科技股份有限公司 2024-07-19 CN disclosed
CN-118324596-A Synthesis method of biaryl compound 新疆大学 2024-07-12 CN disclosed
WO-2024133363-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2024-06-27 WO disclosed
US-20240149262-A1 Immobilization of Molecular Catalysts on Solid Powders via Vapor Deposition of Encapsulating Nano-Layers for Use as Heterogeneous Chemical Catalysts UNIVERSITY OF SOUTH CAROLINA 2024-05-09 US disclosed
WO-2002026665-A2 METHOD FOR PRODUCING ARYL COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 2002-04-04 WO disclosed
WO-2001070753-A1 SULFUR SUBSTITUTED ARYLDIFLUOROMETHYLPHOSPHONIC ACIDS AS PTP-1B INHIBITORS MERCK FROSST CANADA & CO. (CA) 2001-09-27 WO disclosed
WO-2001046203-A1 PHOSPHONIC ACID BIARYL DERIVATIVES AS INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B (PTP-1B) MERCK FROSST CANADA & CO. (CA) 2001-06-28 WO disclosed
US-5561016-A HAVING PHOTOCONDUCTIVE LAYER CONTAINING CHARGE GENERATING MATERIAL, POLYVINYL BUTYRAL BINDER, CHARGE TRANSPORTING MATERIAL AND BIPHENYL(OR DERIVATIVE) ON ELECTROCONDUCTIVE SUPPORT RICOH COMPANY, LTD. (JP) 1996-10-01 US disclosed
EP-0405389-B1 Process for producing an aromatic compound MITSUBISHI CHEM IND (JP) 1995-01-04 EP disclosed
US-5159082-A Catalytic coupling of an aromatic sulfinic acid with an aromatic halogen compound MITSUBISHI KASEI CORPORATION (JP) 1992-10-27 US disclosed
US-4990647-A Process for the preparation of unsymmetric biaryl compounds BAYER AKTIENGESELLSCHAFT (DE) 1991-02-05 US disclosed
EP-0405389-A1 Process for producing an aromatic compound Mitsubishi Chemical Corporation (JP) 1991-01-02 EP disclosed
EP-0341514-A2 Process for the preparation of asymmetrical biaryle compounds BAYER AG (DE) 1989-11-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12510529-B2 Method for determining authenticity and adulteration of marked petroleum hydrocarbons CYP4A11, CYP11B1, CYP11A1 ACHE 3840/4885NPC1 1103/4885RAB9A 3261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.