Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 7/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11438850 | 0.93 | MAPT (0.43) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| SCHEMBL16710359 | 0.93 | ALDH1A1 (0.42) | ALDH1A1ATMTSHRHPGDCA1 | |
| SCHEMBL23553042 | 0.88 | MAPT (0.41) | ALDH1A1CA1CA2NAAAMAPT | |
| SCHEMBL11236918 | 0.88 | ALDH1A1 (0.36) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| SCHEMBL3417815 | 0.88 | CA2 (0.38) | ALDH1A1ATMTSHRCA1CA2 | |
| SCHEMBL21891970 | 0.87 | DGKA (0.42) | ALDH1A1ATMTSHRHPGDNAAA | |
| SCHEMBL26108644 | 0.87 | CA1 (0.33) | ALDH1A1ATMTSHRCA1CA2 | |
| SCHEMBL25964438 | 0.87 | DGKA (0.42) | ALDH1A1ATMTSHRHPGDNAAA | |
| SCHEMBL25964471 | 0.87 | DGKA (0.42) | ALDH1A1ATMTSHRHPGDNAAA | |
| SCHEMBL11443787 | 0.87 | MAPT (0.43) | CA2NAAAMAPTEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960768-A | Acyloxythiophene-carboxamide fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | disclosed |
| US-4871864-A | Carbamoyloxythiophene fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1989-10-03 | — | — | US | disclosed |
| US-4863954-A | Acyloxythiophene-carboxamide fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-05 | — | — | US | disclosed |
| US-4839381-A | FUNGICIDES, PESTICIDES; RICE PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-13 | — | — | US | disclosed |
| US-4767757-A | Acyloxythiophene-carboxamide fungicides, compositions and use | BAYER AKTIENGESELLSCHAFT (DE) | 1988-08-30 | — | — | US | disclosed |
| US-4757085-A | Pharmaceuticals | BAYER AKTIENGESELLSCHAFT (DE) | 1988-07-12 | — | — | US | disclosed |
| EP-0243776-A2 | Carbamoyloxythiophene derivatives | BAYER AG (DE) | 1987-11-04 | — | — | EP | disclosed |
| EP-0241735-A2 | Acyloxythiophene carbon amide | BAYER AG (DE) | 1987-10-21 | — | — | EP | disclosed |