Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 3/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1043659 | 1.00 | CASP1 (0.53) | CASP1ADRB2ADRB1AOC3CYP2D6 | |
| SCHEMBL30799810 | 1.00 | CASP1 (0.53) | CASP1ADRB2ADRB1AOC3CYP2D6 | |
| SCHEMBL29465008 | 0.81 | LMNA (0.52) | CASP1ADRB2ADRB1AOC3CYP2D6 | |
| SCHEMBL29398319 | 0.81 | LMNA (0.52) | CASP1ADRB2ADRB1AOC3CYP2D6 | |
| SCHEMBL28162815 | 0.81 | LMNA (0.52) | CASP1ADRB2ADRB1AOC3CYP2D6 | |
| SCHEMBL24732 | 0.81 | LMNA (0.52) | CASP1ADRB2ADRB1AOC3CYP2D6 | |
| SCHEMBL24733 | 0.81 | LMNA (0.52) | CASP1ADRB2ADRB1AOC3CYP2D6 | |
| SCHEMBL197618 | 0.81 | LMNA (0.52) | CASP1ADRB2ADRB1AOC3CYP2D6 | |
| SCHEMBL29501895 | 0.81 | LMNA (0.52) | CASP1ADRB2ADRB1AOC3CYP2D6 | |
| SCHEMBL28162814 | 0.81 | LMNA (0.52) | CASP1ADRB2ADRB1AOC3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117683820-A | Method for preparing aromatic alpha-hydroxy ketone by utilizing acetohydroxy acid synthase | 厦门大学 | 2024-03-12 | — | — | CN | claimed |
| CN-117683820-A | Method for preparing aromatic alpha-hydroxy ketone by utilizing acetohydroxy acid synthase | 厦门大学 | 2024-03-12 | — | — | CN | disclosed |
| US-20110097766-A1 | 1,2 - ADDITION OF CARBONYL COMPOUNDS USING THE ENZYME YERE | ALBERT-LUDGWIGS-UNIVERSITÄT FREIBURG (DE) | 2011-04-28 | — | — | US | disclosed |
| US-20110097766-A1 | 1,2 - ADDITION OF CARBONYL COMPOUNDS USING THE ENZYME YERE | ALBERT-LUDGWIGS-UNIVERSITÄT FREIBURG (DE) | 2011-04-28 | — | — | US | disclosed |
| US-20110097766-A1 | 1,2 - ADDITION OF CARBONYL COMPOUNDS USING THE ENZYME YERE | ALBERT-LUDGWIGS-UNIVERSITÄT FREIBURG (DE) | 2011-04-28 | — | — | US | disclosed |
| EP-2274434-A1 | 1, 2 ADDITION OF CARBONYL COMPOUNDS USING THE ENZYME YERE | Albert-Ludwigs-Universität Freiburg (DE) | 2011-01-19 | — | — | EP | disclosed |
| WO-2009138439-A1 | 1, 2 – ADDITION OF CARBONYL COMPOUNDS USING THE ENZYME YERE | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2009-11-19 | — | — | WO | disclosed |
| WO-2009138439-A1 | 1, 2 – ADDITION OF CARBONYL COMPOUNDS USING THE ENZYME YERE | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2009-11-19 | — | — | WO | disclosed |
| EP-2119790-A1 | 1,2-addition of carbonyl compounds employing the enzyme YerE | Albert-Ludwigs-Universität Freiburg (DE) | 2009-11-18 | — | — | EP | disclosed |
| EP-2119790-A1 | 1,2-addition of carbonyl compounds employing the enzyme YerE | Albert-Ludwigs-Universität Freiburg (DE) | 2009-11-18 | — | — | EP | disclosed |