Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11752082 | 0.83 | PPARA (0.47) | MEN1KMT2ALMNAHTTHTR2A | |
| SCHEMBL9835351 | 0.80 | MAPK14 (0.42) | MAPK14MEN1KMT2ALMNAMAOA | |
| SCHEMBL10453168 | 0.78 | NPC1 (0.38) | MAPK14MEN1KMT2ALMNAHTT | |
| SCHEMBL11750435 | 0.77 | PPARA (0.50) | MEN1KMT2ALMNAHTTHTR2A | |
| SCHEMBL10204685 | 0.74 | RAB9A (0.63) | MEN1KMT2ALMNAMAOAMAOB | |
| SCHEMBL11540350 | 0.74 | PPARA (0.49) | MAPK14MEN1KMT2ALMNANPSR1 | |
| SCHEMBL21501229 | 0.74 | MAOA (0.44) | MAPK14MEN1KMT2AMAOAMAOB | |
| SCHEMBL11507654 | 0.73 | KMT2A (0.46) | MAPK14MEN1KMT2ALMNAHTT | |
| SCHEMBL11507295 | 0.73 | MEN1 (0.41) | MAPK14MEN1KMT2ALMNAHTT | |
| SCHEMBL11747760 | 0.73 | PPARA (0.47) | MEN1KMT2ALMNAHTTHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4945100-A | Process for the preparation of 1-triazolylethyl ether derivatives | CIBA-GEIGY CORPORATION (US) | 1990-07-31 | — | — | US | disclosed |