Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.47 |
| ▸ | PPARG | P37231 | 7/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | FABP2 | P12104 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11750435 | 0.95 | PPARA (0.50) | PPARAPPARGCYP1A2CYP3A4MEN1 | |
| SCHEMBL11747760 | 0.91 | PPARA (0.47) | PPARAPPARGCYP1A2CYP3A4MEN1 | |
| SCHEMBL11753169 | 0.86 | PPARG (0.40) | PPARAPPARGMEN1MAPTKMT2A | |
| SCHEMBL11757005 | 0.85 | PPARG (0.40) | PPARAPPARGHTR2ASLC6A4LTA4H | |
| SCHEMBL11751258 | 0.85 | PPARG (0.49) | PPARAPPARGCYP1A2MEN1CYP2C19 | |
| SCHEMBL10452432 | 0.83 | MAPK14 (0.43) | PPARAPPARGCYP1A2CYP3A4MEN1 | |
| SCHEMBL11747997 | 0.81 | PPARA (0.47) | PPARAPPARGCYP1A2CYP3A4MEN1 | |
| SCHEMBL11752410 | 0.81 | PPARG (0.43) | PPARAPPARGCYP1A2MAPTCYP2C19 | |
| SCHEMBL11754896 | 0.81 | MEN1 (0.38) | PPARAPPARGMEN1MAPTCYP2C19 | |
| SCHEMBL11752678 | 0.80 | PPARA (0.38) | PPARAPPARGCYP1A2MEN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051173-A | Phenoxyalkanol derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | claimed |
| US-4051173-A | Phenoxyalkanol derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |