Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | THRA | P10827 | 8/20 | 0.53 |
| ▸ | THRB | P10828 | 8/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | STS | P08842 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971794 | 0.88 | THRA (0.60) | L3MBTL1HSD17B3HPGDSMN1; SMN2THRA | |
| SCHEMBL29706047 | 0.86 | THRA (0.63) | HSD17B3THRATHRBSTSHTR2A | |
| SCHEMBL27604328 | 0.85 | HSD17B3 (0.62) | L3MBTL1HSD17B3HPGDSMN1; SMN2THRA | |
| SCHEMBL10452837 | 0.85 | TAAR1 (0.54) | L3MBTL1SMN1; SMN2THRATHRBTAAR1 | |
| Hydrochloric Acid SCHEMBL10451966 | 0.83 | TAAR1 (0.52) | L3MBTL1SMN1; SMN2THRATHRBTAAR1 | |
| SCHEMBL83484 | 0.83 | THRA (0.68) | L3MBTL1HSD17B3HPGDTHRATHRB | |
| SCHEMBL26254861 | 0.82 | HSD17B3 (0.82) | L3MBTL1HSD17B3HPGDSMN1; SMN2STS | |
| SCHEMBL9765140 | 0.81 | L3MBTL1 (0.69) | L3MBTL1SMN1; SMN2TAAR1KMT2ACYP1A2 | |
| SCHEMBL10462264 | 0.80 | CYP4F2 (0.54) | L3MBTL1HPGDTHRATHRBTAAR1 | |
| SCHEMBL4417711 | 0.80 | HSD17B3 (0.67) | L3MBTL1HSD17B3HPGDSMN1; SMN2THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4948809-A | TREATMENT OF AILMENTS DUE TO THROMBOCYTE AGGREGATION OR KIDNEY DYSFUNCTION | BOEHRINGER MANNHEIM GMBH (DE) | 1990-08-14 | — | — | US | disclosed |
| EP-0221344-B1 | SULPHONYL-PHENYL ALKYL AMINES, PROCESS FOR THEIR PREPARATION AND MEDICINES | Roche Diagnostics GmbH (DE) | 1990-05-23 | — | — | EP | disclosed |
| EP-0221344-A1 | Sulphonyl-phenyl alkyl amines, process for their preparation and medicines | Roche Diagnostics GmbH (DE) | 1987-05-13 | — | — | EP | disclosed |