Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 11/20 | 0.60 |
| ▸ | THRB | P10828 | 11/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.53 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.51 |
| ▸ | RARB | P10826 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10453048 | 0.88 | L3MBTL1 (0.59) | THRATHRBL3MBTL1HSD17B3HPGD | |
| SCHEMBL15960542 | 0.86 | THRA (0.79) | THRATHRBHAO1RARB | |
| SCHEMBL83484 | 0.86 | THRA (0.68) | THRATHRBL3MBTL1HSD17B3HAO1 | |
| SCHEMBL24777868 | 0.85 | THRA (0.72) | THRATHRBHAO1RARBHTR2A | |
| SCHEMBL8971789 | 0.83 | THRA (0.60) | THRATHRBL3MBTL1HSD17B3HAO1 | |
| SCHEMBL28908404 | 0.83 | THRA (0.79) | THRATHRBL3MBTL1HSD17B3HAO1 | |
| SCHEMBL12600892 | 0.81 | NPC1 (0.66) | THRATHRBL3MBTL1HSD17B3HAO1 | |
| SCHEMBL30089476 | 0.80 | THRA (0.70) | THRATHRBL3MBTL1HSD17B3HAO1 | |
| SCHEMBL27604328 | 0.80 | HSD17B3 (0.62) | THRATHRBL3MBTL1HSD17B3HPGD | |
| SCHEMBL11267102 | 0.80 | DPP4 (0.51) | THRATHRBL3MBTL1HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596802-B1 | Erythromycin derivatives, their process of preparation and their application as medicaments | ROUSSEL UCLAF (FR) | 1996-03-20 | — | — | EP | disclosed |
| EP-0596802-A1 | Erythromycin derivatives, their process of preparation and their application as medicaments | ROUSSEL UCLAF (FR) | 1994-05-11 | — | — | EP | disclosed |