Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GNRHR | P30968 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9821044 | 0.78 | ESR1 (0.47) | ALDH1A1RORCESR1ESR2NPC1 | |
| SCHEMBL5388017 | 0.77 | ACHE (0.66) | ACHELMNAALDH1A1ESR1ESR2 | |
| SCHEMBL17636591 | 0.76 | ACHE (0.59) | ACHEESR1ESR2L3MBTL1GAA | |
| SCHEMBL6857583 | 0.75 | ACHE (0.63) | ACHEESR1ESR2 | |
| SCHEMBL675031 | 0.74 | ACHE (0.79) | ACHELMNAALDH1A1ESR1ESR2 | |
| SCHEMBL28309510 | 0.72 | ACHE (0.59) | ACHEESR1ESR2 | |
| SCHEMBL28308729 | 0.71 | ACHE (0.58) | ACHEESR1ESR2 | |
| SCHEMBL2996266 | 0.71 | ACHE (0.58) | ACHEESR1ESR2 | |
| SCHEMBL9066251 | 0.71 | ACHE (0.68) | ACHELMNAESR1ESR2 | |
| SCHEMBL9073417 | 0.71 | ACHE (0.58) | ACHEALDH1A1ESR1ESR2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238305-B1 | 4,4-BIS(4-HYDROXYPHENYL)CYCLOHEXANECARBOXYLIC ACID DERIVATIVES AND PROCESS FOR PREPARING SAME | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-05-23 | — | — | EP | claimed |
| US-4755616-A | 4,4-bis(4-hydroxyphenyl)cyclohexanecarboxylic acid derivatives and process for preparing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1988-07-05 | — | — | US | claimed |
| EP-0238305-A1 | 4,4-Bis(4-hydroxyphenyl)cyclohexanecarboxylic acid derivatives and process for preparing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1987-09-23 | — | — | EP | claimed |
| JP-63010745-A | — | — | None | — | — | JP | disclosed |
| EP-0238305-B1 | 4,4-BIS(4-HYDROXYPHENYL)CYCLOHEXANECARBOXYLIC ACID DERIVATIVES AND PROCESS FOR PREPARING SAME | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-05-23 | — | — | EP | disclosed |
| US-4814488-A | STARTING MATERIALS FOR POLYMERS | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1989-03-21 | — | — | US | disclosed |
| US-4755616-A | 4,4-bis(4-hydroxyphenyl)cyclohexanecarboxylic acid derivatives and process for preparing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1988-07-05 | — | — | US | disclosed |
| JP-S6310745-A | 4,4-BIS(4-HYDROXYPHENYL)-(CYCLOHEXANECARBOXYLIC ACID DERIVATIVE AND PRODUCTION THEREOF | MITSUI TOATSU CHEM INC | 1988-01-18 | — | — | JP | disclosed |
| EP-0238305-A1 | 4,4-Bis(4-hydroxyphenyl)cyclohexanecarboxylic acid derivatives and process for preparing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1987-09-23 | — | — | EP | disclosed |