Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10410332 | 0.86 | ATM (0.43) | ESR2RORCATML3MBTL1MIF | |
| SCHEMBL10410215 | 0.86 | ATM (0.43) | ESR2RORCATML3MBTL1MIF | |
| SCHEMBL10411315 | 0.86 | ATM (0.43) | ESR2RORCATML3MBTL1MIF | |
| SCHEMBL8907518 | 0.83 | ESR1 (0.43) | ESR1ESR2L3MBTL1ALDH1A1CA12 | |
| SCHEMBL9821032 | 0.80 | ESR2 (0.53) | ESR1ESR2RORCCA12CA1 | |
| SCHEMBL10453072 | 0.78 | ACHE (0.51) | ESR1ESR2RORCATML3MBTL1 | |
| SCHEMBL10453324 | 0.78 | ESR1 (0.39) | ESR1ESR2ATML3MBTL1MIF | |
| SCHEMBL30249996 | 0.75 | ALDH1A1 (0.46) | ATML3MBTL1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7183973 | 0.74 | ESR2 (0.55) | ESR1ESR2ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL25141743 | 0.73 | ESR2 (0.55) | ESR1ESR2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238305-B1 | 4,4-BIS(4-HYDROXYPHENYL)CYCLOHEXANECARBOXYLIC ACID DERIVATIVES AND PROCESS FOR PREPARING SAME | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-05-23 | — | — | EP | claimed |
| US-4755616-A | 4,4-bis(4-hydroxyphenyl)cyclohexanecarboxylic acid derivatives and process for preparing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1988-07-05 | — | — | US | claimed |
| EP-0238305-A1 | 4,4-Bis(4-hydroxyphenyl)cyclohexanecarboxylic acid derivatives and process for preparing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1987-09-23 | — | — | EP | claimed |
| EP-0240362-B1 | PROCESS FOR THE PREPARATION OF 4'-HYDROXYBIPHENYL-4-CARBOXYLIC ACID | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-12-11 | — | — | EP | disclosed |
| EP-0238305-B1 | 4,4-BIS(4-HYDROXYPHENYL)CYCLOHEXANECARBOXYLIC ACID DERIVATIVES AND PROCESS FOR PREPARING SAME | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-05-23 | — | — | EP | disclosed |
| US-4814488-A | STARTING MATERIALS FOR POLYMERS | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1989-03-21 | — | — | US | disclosed |
| US-4755616-A | 4,4-bis(4-hydroxyphenyl)cyclohexanecarboxylic acid derivatives and process for preparing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1988-07-05 | — | — | US | disclosed |
| US-4755617-A | Process for the preparation of 4'-hydroxybiphenyl-4-carboxyl acid | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1988-07-05 | — | — | US | disclosed |
| EP-0240362-A2 | Process for the preparation of 4'-hydroxybiphenyl-4-carboxylic acid | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1987-10-07 | — | — | EP | disclosed |
| EP-0238305-A1 | 4,4-Bis(4-hydroxyphenyl)cyclohexanecarboxylic acid derivatives and process for preparing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1987-09-23 | — | — | EP | disclosed |