Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.61 |
| ▸ | CASP1 | P29466 | 8/20 | 0.58 |
| ▸ | CTSK | P43235 | 3/20 | 0.57 |
| ▸ | LTA4H | P09960 | 2/20 | 0.56 |
| ▸ | MME | P08473 | 1/20 | 0.55 |
| ▸ | ECE1 | P42892 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10868042 | 0.94 | CAPN1 (0.58) | CAPN1CASP1CTSKLTA4HMME | |
| SCHEMBL9656020 | 0.91 | CAPN1 (0.62) | CAPN1CASP1CTSK | |
| SCHEMBL11697381 | 0.90 | CASP1 (0.56) | CAPN1CASP1CTSK | |
| SCHEMBL9088735 | 0.88 | CAPN1 (0.72) | CAPN1CTSKMMEECE1 | |
| SCHEMBL7281206 | 0.88 | CAPN1 (0.72) | CAPN1CTSKMMEECE1 | |
| SCHEMBL5484209 | 0.88 | CAPN1 (0.72) | CAPN1CTSKMMEECE1 | |
| SCHEMBL10967811 | 0.88 | CAPN1 (0.72) | CAPN1CTSKMMEECE1 | |
| SCHEMBL31397615 | 0.88 | CAPN1 (0.72) | CAPN1CTSKMMEECE1 | |
| SCHEMBL10789378 | 0.88 | MME (0.62) | CASP1CTSKMMEECE1 | |
| SCHEMBL8823914 | 0.87 | CAPN1 (0.78) | CAPN1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4894464-A | ARTIFICIAL SWEETENERS | PFIZER INC. (US) | 1990-01-16 | — | — | US | disclosed |
| US-4855454-A | CHEMICAL INTERMEDIATES; SWEETENERS | PFIZER INC. (US) | 1989-08-08 | — | — | US | disclosed |
| US-4804782-A | ARTIFICIAL SWEETENER | PFIZER, INC. (US) | 1989-02-14 | — | — | US | disclosed |
| EP-0034876-B1 | BRANCHED AMIDES OF L-ASPARTYL-D-AMINO ACID DIPEPTIDES AND COMPOSITIONS THEREOF | PFIZER INC. (US) | 1984-08-29 | — | — | EP | disclosed |
| US-4411925-A | STABLE SWEETENERS | PFIZER INC. (US) | 1983-10-25 | — | — | US | disclosed |
| EP-0034876-A2 | Branched amides of L-aspartyl-D-amino acid dipeptides and compositions thereof | PFIZER INC. (US) | 1981-09-02 | — | — | EP | disclosed |